Gene drive technology offers the promise for a high-impact, cost-effective, and durable
method to control malaria transmission that would make a significant contribution to …

Gene drive-modified mosquitoes (GDMMs) are being developed as possible new tools to
prevent transmission of malaria and other mosquito-borne diseases. To date no GDMMs …

Reducing the incidence of malaria has been a public health priority for nearly a century.
New technologies and associated vector control strategies play an important role in the …

Mosquitoes containing gene drive systems are being developed as complementary tools to
prevent transmission of malaria and other mosquito-borne diseases. As with any new tool …

Background Gene drive mosquitoes have been proposed as a possible means to reduce the
transmission of malaria in Africa. Because this technology has no prior use-history at this …

1. OBJECTIVE THE FOLLOWING RECOMMENDATIONS represent the response of a group
of involved scientists to the need for guidance to aid researchers, government authorities …

Gene drive mosquitoes are a novel approach to vector control being developed to help
tackle malaria. A gene drive increases the frequency of a desired gene and its phenotypic …

A Cas9/guide RNA-based gene drive strain, AgNosCd-1, was developed to deliver
antiparasite effector molecules to the malaria vector mosquito, Anopheles gambiae. The …

Despite impressive progress, malaria continues to impose a substantial burden of mortality
and morbidity, particularly in sub-Saharan Africa, and new tools will be needed to achieve …

Genetic modification (GM) of mosquitoes (which renders them genetically modified
organisms, GMOs) offers opportunities for controlling malaria. Transgenic strains of …