Soon after HIV was discovered as the cause of AIDS in 1983–1984, there was an
expectation that a preventive vaccine would be rapidly developed. In trying to achieve that …

Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a
worldwide epidemic, with over 35 million people infected currently. Therefore, the …

An efficacious HIV-1 vaccine is regarded as the best way to halt the ongoing HIV-1
epidemic. However, despite significant efforts to develop a safe and effective vaccine, the …

The greatest hope for controlling the expanding HIV epidemic is the development of a
preventive HIV vaccine. Despite almost twenty years of effort, the search for an effective HIV …

Twenty years after its recognition, HIV/AIDS has become the most important infectious
disease globally and the leading cause of death in Africa. A preventive vaccine represents …

A global human immunodeficiency virus‐1 (HIV‐1) vaccine will have to elicit immune
responses capable of providing protection against a tremendous diversity of HIV‐1 variants …

The development of a safe, effective and globally affordable HIV vaccine offers the best
hope for the future control of the HIV-1 pandemic. Since 1987, scores of candidate HIV-1 …

The global HIV epidemic continues to expand, exceeding previous predictions and causing
tremendous suffering. An effective vaccine represents the best hope to curtail the HIV …

HIV-1 infection and its progression to AIDS remains a significant global health challenge,
particularly for low-income countries. Developing a vaccine to prevent HIV-1 infections has …

An effective HIV-1 vaccine is a global health priority but has remained elusive for more than
40 years. Key scientific hurdles that have hampered vaccine development are the …