Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

MC Papadopoulos, JL Bennett… - Nature Reviews …, 2014 - nature.com
Neuromyelitis optica (NMO) is an autoimmune disease of the CNS that is characterized by
inflammatory demyelinating lesions in the spinal cord and optic nerve, potentially leading to …

Pharmacotherapy for neuromyelitis optica spectrum disorders: current management and future options

N Collongues, E Ayme-Dietrich, L Monassier… - Drugs, 2019 - Springer
Neuromyelitis optica (NMO) is an inflammatory and demyelinating disease of the central
nervous system. Although the prevalence of NMO is low, the rapid and severe impairment …

Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies

E Carnero Contentti, J Correale - Journal of neuroinflammation, 2021 - Springer
Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central
nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis …

Hope for patients with neuromyelitis optica spectrum disorders—from mechanisms to trials

SJ Pittock, A Zekeridou, BG Weinshenker - Nature Reviews Neurology, 2021 - nature.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

B lymphocytes in neuromyelitis optica

JL Bennett, KC O'Connor, A Bar-Or… - Neuroimmunology & …, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that
predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of …

Current and future treatment approaches for neuromyelitis optica

N Collongues, J de Seze - Therapeutic advances in …, 2011 - journals.sagepub.com
Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system (CNS)
characterized by severe attacks of optic neuritis and myelitis, and which, unlike multiple …

Acute and chronic management of neuromyelitis optica spectrum disorder

E Sherman, MH Han - Current treatment options in neurology, 2015 - Springer
Opinion statement Neuromyelitis optica and neuromyelitis optica spectrum disorder
(NMO/NMOSD) is a rare but clinically aggressive demyelinating disease of the central …

Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies

J Ratelade, AS Verkman - The international journal of biochemistry & cell …, 2012 - Elsevier
Neuromyelitis optica (NMO) is an autoimmune 'aquaporinopathy'of the central nervous
system that causes inflammatory demyelinating lesions primarily in spinal cord and optic …

Advances in the treatment of neuromyelitis optica spectrum disorder

AI Wallach, M Tremblay, I Kister - Neurologic Clinics, 2021 - neurologic.theclinics.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare, relapsing-remitting
neuroinflammatory disorder of the central nervous system (CNS) usually associated with …

Anti–Aquaporin‐4 monoclonal antibody blocker therapy for neuromyelitis optica

L Tradtrantip, H Zhang, S Saadoun… - Annals of …, 2012 - Wiley Online Library
Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the
central nervous system. Circulating autoantibodies (NMO‐immunoglobulin [Ig] G) against …