Design and simulation of DNA, RNA and hybrid protein–nucleic acid nanostructures with oxView

J Bohlin, M Matthies, E Poppleton, J Procyk, A Mallya… - Nature protocols, 2022 - nature.com
Molecular simulation has become an integral part of the DNA/RNA nanotechnology
research pipeline. In particular, understanding the dynamics of structures and single …

OxDNA. org: a public webserver for coarse-grained simulations of DNA and RNA nanostructures

E Poppleton, R Romero, A Mallya… - Nucleic acids …, 2021 - academic.oup.com
OxDNA and oxRNA are popular coarse-grained models used by the DNA/RNA
nanotechnology community to prototype, analyze and rationalize designed DNA and RNA …

Design, optimization and analysis of large DNA and RNA nanostructures through interactive visualization, editing and molecular simulation

E Poppleton, J Bohlin, M Matthies… - Nucleic acids …, 2020 - academic.oup.com
This work seeks to remedy two deficiencies in the current nucleic acid nanotechnology
software environment: the lack of both a fast and user-friendly visualization tool and a …

Adenita: interactive 3D modelling and visualization of DNA nanostructures

E De Llano, H Miao, Y Ahmadi, AJ Wilson… - Nucleic acids …, 2020 - academic.oup.com
DNA nanotechnology is a rapidly advancing field, which increasingly attracts interest in
many different disciplines, such as medicine, biotechnology, physics and biocomputing. The …

MrDNA: a multi-resolution model for predicting the structure and dynamics of DNA systems

C Maffeo, A Aksimentiev - Nucleic acids research, 2020 - academic.oup.com
Although the field of structural DNA nanotechnology has been advancing with an
astonishing pace, de novo design of complex 3D nanostructures and functional devices …

Tacoxdna: A user‐friendly web server for simulations of complex DNA structures, from single strands to origami

A Suma, E Poppleton, M Matthies… - Journal of …, 2019 - Wiley Online Library
Simulations of nucleic acids at different levels of structural details are increasingly used to
complement and interpret experiments in different fields, from biophysics to medicine and …

Simulation and modeling of nucleic acid structure, dynamics and interactions

TE Cheatham III - Current opinion in structural biology, 2004 - Elsevier
In moving towards the simulation of larger nucleic acid assemblies over longer timescales
that include more accurate representations of the environment, we are nearing the end of an …

Quantitative prediction of 3D solution shape and flexibility of nucleic acid nanostructures

DN Kim, F Kilchherr, H Dietz, M Bathe - Nucleic acids research, 2012 - academic.oup.com
DNA nanotechnology enables the programmed synthesis of intricate nanometer-scale
structures for diverse applications in materials and biological science. Precise control over …

Designer nanoscale DNA assemblies programmed from the top down

R Veneziano, S Ratanalert, K Zhang, F Zhang, H Yan… - Science, 2016 - science.org
INTRODUCTION Synthetic DNA can be programmed by using canonical Watson-Crick base
pairing to form highly structured nanometer-scale assemblies that rival many natural protein …

Coarse-graining DNA for simulations of DNA nanotechnology

JPK Doye, TE Ouldridge, AA Louis… - Physical Chemistry …, 2013 - pubs.rsc.org
To simulate long time and length scale processes involving DNA it is necessary to use a
coarse-grained description. Here we provide an overview of different approaches to such …