Inadequate perioperative pain is, unfortunately, frequent, and has clinically relevant
consequences, including decreased patient satisfaction, delayed postoperative mobilization …

Postoperative pain remains a challenging problem, which requires a proactive approach
using a variety of treatment modalities to obtain an optimal outcome with respect to …

Background Multimodal analgesia is increasingly considered routine practice in joint
arthroplasties, but supportive large-scale data are scarce. The authors aimed to determine …

Orthopedic surgery was one of the first specialties to embrace multimodal analgesia and
incorporate it into practice more than a decade ago. Orthopedic surgeries are considered to …

EDITORIAL VIEWS and pain scores assessed during well-defined movement relevant for
recovery from the procedure in question. importantly, the goal of any pain therapy should be …

Background Figure 1 shows the pathways of nociceptive stimuli, including those conducting
pain, from the site of surgical injury passing through the peripheral nervous system to the …

Multimodal analgesia for controlling acute postoperative pai... : Current Opinion in
Anesthesiology Multimodal analgesia for controlling acute postoperative pain : Current Opinion …

Multimodal analgesia (MMA) involves the use of additive or synergistic combinations of
analgesics to achieve clinically required analgesia while minimizing significant side effects …

Advances in our understanding of the pathophysiology of postoperative pain have led to the
development of effective perioperative analgesic regimens [1]. It is now well recognized that …

DESPITE recent advances in our understanding of the physiology of acute pain, the
development of new opioid and nonopioid analgesics and novel methods of drug delivery …