[PDF][PDF] The Role of Ferroptosis in Inflammatory Bowel Disease: Mechanisms and Therapeutic Implications

Q Yan - Qeios, 2024 - qeios-uploads.s3.eu-west-1 …
Abstract Inflammatory Bowel Disease (IBD), encompassing Crohn's disease and ulcerative
colitis, is characterized by chronic inflammation of the gastrointestinal tract, with an …

Emerging pathological engagement of ferroptosis in gut diseases

W Gao, T Zhang, H Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is mainly
characterized by chronic and progressive inflammation that damages the gastrointestinal …

Advances in Ferroptosis and Inflammatory Bowel Disease

Y PU, J ZHANG, W DONG - Chinese General Practice, 2023 - chinagp.net
Inflammatory bowel disease (IBD) is a group of chronic non-specific gastrointestinal
inflammatory conditions, whose pathogenic factors and pathogenesis may be related to …

Role of ferroptosis in the pathogenesis and as a therapeutic target of inflammatory bowel disease

DKW Ocansey, J Yuan, Z Wei… - International …, 2023 - spandidos-publications.com
Ferroptosis, a novel form of regulated cell death, is characterized by the accumulation of
labile iron and lipid peroxidation, and the excessive production of reactive oxygen species …

Research progress of ferroptosis and inflammatory bowel disease

B Ma, X Hu, X Ai, Y Zhang - BioMetals, 2024 - Springer
Inflammatory bowel disease (IBD) is a non-specific chronic inflammatory disorder of the
gastrointestinal tract, imposing significant burdens on both society and individuals. As a new …

The emerging role of ferroptosis in intestinal disease

S Xu, Y He, L Lin, P Chen, M Chen, S Zhang - Cell Death & Disease, 2021 - nature.com
Ferroptosis is a newly recognised type of regulated cell death (RCD) characterised by iron-
dependent accumulation of lipid peroxidation. It is significantly distinct from other RCDs at …

Ferroptosis as a therapeutic target for inflammation-related intestinal diseases

X Zhang, Y Ma, G Lv, H Wang - Frontiers in Pharmacology, 2023 - frontiersin.org
Ferroptosis is an iron-dependent programmed cell death characterized by reactive oxygen
species-induced lipid peroxidation and resultant membrane damage. Recent research has …

[HTML][HTML] Ferroptosis in ulcerative colitis: Potential mechanisms and promising therapeutic targets

D Long, C Mao, Y Huang, Y Xu, Y Zhu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Ulcerative colitis (UC) is a complex immune-mediated chronic inflammatory bowel disease.
It is mainly characterized by diffuse inflammation of the colonic and rectal mucosa with …

The impacts of iron overload and ferroptosis on intestinal mucosal homeostasis and inflammation

C Huo, G Li, Y Hu, H Sun - International Journal of Molecular Sciences, 2022 - mdpi.com
Intestinal homeostasis is maintained through the interplay of the intestinal mucosa, local and
systemic immune factors, and the microbial content of the gut. Iron is a trace mineral in most …

Inhibiting ferroptosis: a novel approach for ulcerative colitis therapeutics

J Huang, J Zhang, J Ma, J Ma, J Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Ulcerative colitis (UC) is a recurrent and persistent nonspecific inflammatory bowel disease
(IBD) that greatly affects human survival and social wealth. Despite the advances in the …