Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

F Liesecke, D Daudu, R Dugé de Bernonville… - Scientific reports, 2018 - nature.com
Co-expression networks are essential tools to infer biological associations between gene
products and predict gene annotation. Global networks can be analyzed at the transcriptome …

Comparative study of RNA-seq- and Microarray-derived coexpression networks in Arabidopsis thaliana

FM Giorgi, C Del Fabbro, F Licausi - Bioinformatics, 2013 - academic.oup.com
Motivation: Coexpression networks are data-derived representations of genes behaving in a
similar way across tissues and experimental conditions. They have been used for …

Improved gene co-expression network quality through expression dataset down-sampling and network aggregation

F Liesecke, JO De Craene, S Besseau… - Scientific reports, 2019 - nature.com
Large-scale gene co-expression networks are an effective methodology to analyze sets of
co-expressed genes and discover new gene functions or associations. Distances between …

Comparison of co-expression measures: mutual information, correlation, and model based indices

L Song, P Langfelder, S Horvath - BMC bioinformatics, 2012 - Springer
Background Co-expression measures are often used to define networks among genes.
Mutual information (MI) is often used as a generalized correlation measure. It is not clear …

Maximizing capture of gene co-expression relationships through pre-clustering of input expression samples: an Arabidopsis case study

FA Feltus, SP Ficklin, SM Gibson, MC Smith - BMC systems biology, 2013 - Springer
Background In genomics, highly relevant gene interaction (co-expression) networks have
been constructed by finding significant pair-wise correlations between genes in expression …

Canonical correlation analysis for RNA-seq co-expression networks

S Hong, X Chen, L Jin, M Xiong - Nucleic acids research, 2013 - academic.oup.com
Digital transcriptome analysis by next-generation sequencing discovers substantial mRNA
variants. Variation in gene expression underlies many biological processes and holds a key …

Evaluation and improvement of the regulatory inference for large co-expression networks with limited sample size

W Guo, CPG Calixto, N Tzioutziou, P Lin, R Waugh… - BMC systems …, 2017 - Springer
Background Co-expression has been widely used to identify novel regulatory relationships
using high throughput measurements, such as microarray and RNA-seq data. Evaluation …

Distance correlation application to gene co-expression network analysis

J Hou, X Ye, W Feng, Q Zhang, Y Han, Y Liu, Y Li… - BMC …, 2022 - Springer
Background To construct gene co-expression networks, it is necessary to evaluate the
correlation between different gene expression profiles. However, commonly used correlation …

Functional Network Construction in Arabidopsis Using Rule-Based Machine Learning on Large-Scale Data Sets

GW Bassel, E Glaab, J Marquez, MJ Holdsworth… - The Plant …, 2011 - academic.oup.com
The meta-analysis of large-scale postgenomics data sets within public databases promises
to provide important novel biological knowledge. Statistical approaches including correlation …

Co-expression networks for plant biology: why and how

X Rao, RA Dixon - Acta biochimica et biophysica Sinica, 2019 - academic.oup.com
Co-expression network analysis is one of the most powerful approaches for interpretation of
large transcriptomic datasets. It enables characterization of modules of co-expressed genes …