Examining the regional physiology of the transplant kidney during normothermic machine perfusion.

TD Adams - 2021 - repository.cam.ac.uk
Ischaemia-reperfusion injury (IRI) is an unavoidable consequence of deceased-donor
kidney transplantation that has a profound effect upon both immediate and long-term graft …

[HTML][HTML] Utilizing pathophysiological concepts of ischemia-reperfusion injury to design renoprotective strategies and therapeutic interventions for normothermic ex vivo …

B Ogurlu, TL Hamelink, IM Van Tricht… - American Journal of …, 2024 - Elsevier
Normothermic machine perfusion (NMP) has emerged as a promising tool for the
preservation, viability assessment, and repair of deceased-donor kidneys prior to …

Investigating the Impact of Temperature and Oxygen on Preservation Injury after Ex vivo Kidney Perfusion

LI Mazilescu - 2021 - search.proquest.com
Kidney transplantation improves the lives of patients with end-stage kidney disease, and
extends their life expectancy. Ex vivo machine perfusion has been extensively explored in …

[HTML][HTML] The future of marginal kidney repair in the context of normothermic machine perfusion

JR DiRito, SA Hosgood, GT Tietjen… - American Journal of …, 2018 - Elsevier
Normothermic machine perfusion (NMP) is a technique that utilizes extracorporeal
membrane oxygenation to recondition and repair kidneys at near body temperature prior to …

Subnormothermic Oxygenated Machine Perfusion (24 h) in DCD Kidney Transplantation

N Abraham, Q Gao, R Kahan, IS Alderete… - Transplantation …, 2024 - journals.lww.com
Background. Ex vivo kidney perfusion is an evolving platform that demonstrates promise in
preserving and rehabilitating the kidney grafts. Despite this, there is little consensus on the …

Normothermic ex vivo perfusion of deceased donor kidneys and its clinical potential in kidney transplantation outcomes

M Unes, K Kurashima, Y Caliskan… - … Journal of Artificial …, 2023 - journals.sagepub.com
In recent years, normothermic machine perfusion (NMP) has emerged in conversation
surrounding organ preservation and transplantation techniques with the goal of improving …

Subnormothermic ex vivo porcine kidney perfusion improves energy metabolism: analysis using 31P magnetic resonance spectroscopic imaging

T Agius, J Songeon, A Klauser, F Allagnat… - Transplantation …, 2022 - journals.lww.com
Background. The ideal preservation temperature for donation after circulatory death kidney
grafts is unknown. We investigated whether subnormothermic (22 C) ex vivo kidney machine …

Sub-Normothermic Ex-Vivo Perfusion of Porcine Kidney Grafts Improves Energy Metabolism: 31 P-MRSI Analysis

J Songeon, T Agius, A Klauser, G Longchamp… - archive.ismrm.org
Improved preservation strategies for the storage of graft collected after circulatory death
could increase the number of kidneys available and improve patient survival. Warm (22 and …

Studies of normothermic machine perfusion in human kidney transplantation

T Elliott - 2023 - repository.cam.ac.uk
Normothermic machine perfusion (NMP) of human kidneys is a new preservation technique
that allows for the assessment and treatment of kidneys prior to transplantation. However …

[HTML][HTML] Defining the optimal duration for normothermic regional perfusion in the kidney donor: A porcine preclinical study

T Kerforne, G Allain, S Giraud, D Bon… - American Journal of …, 2019 - Elsevier
Kidneys from donation after circulatory death (DCD) are highly sensitive to ischemia-
reperfusion injury and thus require careful reconditioning, such as normothermic regional …