[HTML][HTML] Biochemical basis and metabolic interplay of redox regulation

L Zhang, X Wang, R Cueto, C Effi, Y Zhang, H Tan… - Redox biology, 2019 - Elsevier
Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

New insight into the role of reactive oxygen species (ROS) in cellular signal-transduction processes

EG Russell, TG Cotter - International review of cell and molecular biology, 2015 - Elsevier
Reactive oxygen species (ROS) were once considered to be deleterious agents,
contributing to a vast range of pathologies. But, now their protective effects are being …

Redox signaling at the crossroads of human health and disease

J Zuo, Z Zhang, M Luo, L Zhou, EC Nice, W Zhang… - MedComm, 2022 - Wiley Online Library
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Modulation of reactive oxygen species in health and disease

S Habtemariam - Antioxidants, 2019 - mdpi.com
In diverse living organisms, signaling within the cell, chemical communication between cells
or simply the fate of cells to survive or die is largely dependent on the intricate balance of …

Redox metabolism: ROS as specific molecular regulators of cell signaling and function

C Lennicke, HM Cochemé - Molecular Cell, 2021 - cell.com
Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Hormesis and oxidative distress: Pathophysiology of reactive oxygen species and the open question of antioxidant modulation and supplementation

M Nitti, B Marengo, AL Furfaro, MA Pronzato… - Antioxidants, 2022 - mdpi.com
Alterations of redox homeostasis leads to a condition of resilience known as hormesis that is
due to the activation of redox-sensitive pathways stimulating cell proliferation, growth …

[HTML][HTML] ROS function in redox signaling and oxidative stress

M Schieber, NS Chandel - Current biology, 2014 - cell.com
Oxidative stress refers to elevated intracellular levels of reactive oxygen species (ROS) that
cause damage to lipids, proteins and DNA. Oxidative stress has been linked to a myriad of …

Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications

AI Casas, VTV Dao, A Daiber, GJ Maghzal… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Enhanced levels of reactive oxygen species (ROS) have been associated with
different disease states. Most attempts to validate and exploit these associations by chronic …

Biological and physiological role of reactive oxygen species–the good, the bad and the ugly

L Zuo, T Zhou, BK Pannell, AC Ziegler… - Acta …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …