This study aims to evaluate the causal association of blood pressure (BP) with
cardiovascular diseases (CVDs). Two-sample Mendelian randomization was performed …

Importance Hypertension remains the major cardiovascular disease risk factor globally, but
variability in measured blood pressure may result in suboptimal management. Whether …

Recent genome-wide association studies have identified genetic variants associated with
blood pressure (BP). We investigated whether genetic risk scores (GRSs) constructed of …

Background: High blood pressure (BP) is a major risk factor for cardiovascular diseases
(CVDs), the leading cause of mortality worldwide. Both heritable and lifestyle risk factors …

Observational studies exploring whether there is a nonlinear effect of blood pressure on
cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be …

Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To
investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial …

Blood pressure (BP) is a heritable trait with multiple environmental and genetic
contributions, with current heritability estimates from twin and family studies being~ 40 …

Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure …

Objective: We aimed to estimate the effect of blood pressure (BP) traits and BP-lowering
medications (via genetic proxies) on peripheral artery disease. Approach and Results …

Importance Modifiable risk factors for valvular heart disease remain largely unknown, which
limits prevention and treatment. Objective To assess the association between systolic blood …