Host matters: medicinal leech digestive-tract symbionts and their pathogenic potential

JN Marden, EA McClure, L Beka, J Graf - Frontiers in Microbiology, 2016 - frontiersin.org
Digestive-tract microbiota exert tremendous influence over host health. Host-symbiont model
systems are studied to investigate how symbioses are initiated and maintained, as well as to …

Macrobdella decora: Old World Leech Gut Microbial Community Structure Conserved in a New World Leech

EA McClure, MC Nelson, A Lin… - Applied and Environmental …, 2021 - Am Soc Microbiol
Leeches are found in terrestrial, aquatic, and marine habitats on all continents.
Sanguivorous leeches have been used in medicine for millennia. Modern scientific uses …

Metagenomic analysis of the medicinal leech gut microbiota

MA Maltz, L Bomar, P Lapierre, HG Morrison… - Frontiers in …, 2014 - frontiersin.org
There are trillions of microbes found throughout the human body and they exceed the
number of eukaryotic cells by 10-fold. Metagenomic studies have revealed that the majority …

Investigation into the Physiologies of Aeromonas veronii in vitro and Inside the Digestive Tract of the Medicinal Leech Using RNA-seq

L Bomar, J Graf - The Biological Bulletin, 2012 - journals.uchicago.edu
Host-associated microbial communities are widespread in nature and vital to the health and
fitness of the host. Deciphering the physiology of the microbiome in vivo is critical to …

Culture-independent characterization of the digestive-tract microbiota of the medicinal leech reveals a tripartite symbiosis

PL Worthen, CJ Gode, J Graf - Applied and environmental …, 2006 - Am Soc Microbiol
Culture-based studies of the microbial community within the gut of the medicinal leech have
typically been focused on various Aeromonas species, which were believed to be the sole …

Bacterial symbioses of the medicinal leech Hirudo verbana

MC Nelson, J Graf - Gut Microbes, 2012 - Taylor & Francis
Gastrointestinal microbiomes play important roles in the health and nutrition of animals and
humans. The medicinal leech, Hirudo verbana, serves as a powerful model for the study of …

Characterization of shed medicinal leech mucus reveals a diverse microbiota

BM Ott, A Rickards, L Gehrke, RVM Rio - Frontiers in Microbiology, 2015 - frontiersin.org
Microbial transmission through mucosal-mediated mechanisms is widespread throughout
the animal kingdom. One example of this occurs with Hirudo verbana, the medicinal leech …

Identification of Aeromonas veronii Genes Required for Colonization of the Medicinal Leech, Hirudo verbana

AC Silver, NM Rabinowitz, S Küffer… - Journal of …, 2007 - Am Soc Microbiol
Most digestive tracts contain a complex consortium of beneficial microorganisms, making it
challenging to tease apart the molecular interactions between symbiont and host. The …

A tale of transmission: Aeromonas veronii activity within leech-exuded mucus

BM Ott, AM Dacks, KJ Ryan… - Applied and Environmental …, 2016 - Am Soc Microbiol
Transmission, critical to the establishment and persistence of host-associated microbiotas,
also exposes symbionts to new environmental conditions. With horizontal transmission …

Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii

A Tasiemski, F Massol, V Cuvillier-Hot… - Scientific Reports, 2015 - nature.com
The medicinal leech has established a long-term mutualistic association with Aeromonas
veronii, a versatile bacterium which can also display free-living waterborne and fish-or …