[HTML][HTML] Anticholinergic load: A commonly neglected and preventable risk to cognition during schizophrenia treatment?

C Martínez-Cao, A García-Fernández… - Schizophrenia Research …, 2024 - Elsevier
Background Cognitive impairment is a widespread feature of schizophrenia, affecting nearly
80% of patients. Prior research has linked the anticholinergic burden of psychiatric …

Anticholinergic medication burden–associated cognitive impairment in schizophrenia

YB Joshi, ML Thomas, DL Braff… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Many psychotropic medications used to treat schizophrenia have significant
anticholinergic properties, which are linked to cognitive impairment and dementia risk in …

Comparative analysis of anticholinergic burden scales to explain iatrogenic cognitive impairment in schizophrenia: results from the multicenter FACE-SZ cohort

N Vidal, P Roux, M Urbach, C Belmonte… - Frontiers in …, 2024 - frontiersin.org
Aim The anticholinergic properties of medications are associated with poorer cognitive
performance in schizophrenia. Numerous scales have been developed to assess …

The impact of medication anticholinergic burden on cognitive performance in people with schizophrenia

M San Ang, NAA Rashid, M Lam… - Journal of clinical …, 2017 - journals.lww.com
Background Cognitive deficits are prevalent in people with schizophrenia and associated
with functional impairments. In addition to antipsychotics, pharmacotherapy in schizophrenia …

The effect of anticholinergic burden on cognitive and daily living functions in patients with schizophrenia

SJ Kim, D Jung, JC Shim, JJ Moon, DW Jeon… - Asian Journal of …, 2019 - Elsevier
Objective This study aimed to explore the association between medication-associated
anticholinergic burden and cognitive and daily living functions in patients with …

Anticholinergic burden and cognitive performance in patients with schizophrenia: a systematic literature review

R Georgiou, D Lamnisos, K Giannakou - Frontiers in psychiatry, 2021 - frontiersin.org
Objective: Cognitive impairment in schizophrenia forms the key cause of the disease's
disability, leading to serious functional, and socioeconomic implications. Dopaminergic …

Cognitive burden of anticholinergic medications in psychotic disorders

S Eum, SK Hill, LH Rubin, RM Carnahan, JL Reilly… - Schizophrenia …, 2017 - Elsevier
Background Patients with psychotic disorders are often treated with numerous medications,
many of which have anticholinergic activity. We assessed cognition in relation to the …

Effects of antipsychotic and anticholinergic medications on cognition in chronic patients with schizophrenia

C Haddad, P Salameh, H Sacre, JP Clément, B Calvet - BMC psychiatry, 2023 - Springer
Background Patients with psychosis frequently use a variety of psychotropic medicines,
many of which have anticholinergic effects that can impair cognition. Therefore, this study …

The impact of anticholinergic burden on functional capacity in persons with schizophrenia across the adult life span

WU Khan, Z Ghazala, HJ Brooks… - Schizophrenia …, 2021 - academic.oup.com
Anticholinergic burden (ACB) from medications impairs cognition in schizophrenia.
Cognition is a predictor of functional capacity; however, little is known about ACB effect on …

The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia

S Vinogradov, M Fisher, H Warm… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: Schizophrenia is treated with medications that raise serum anticholinergic activity
and are known to adversely affect cognition. The authors examined the relationship between …