Breast cancer immunobiology driving immunotherapy: vaccines and immune checkpoint blockade
LA Emens - Expert review of anticancer therapy, 2012 - Taylor & Francis
Breast cancer is immunogenic, and infiltrating immune cells in primary breast tumors convey
important clinical prognostic and predictive information. Furthermore, the immune system is …
important clinical prognostic and predictive information. Furthermore, the immune system is …
Breast cancer immunotherapy: an update
I Makhoul, M Atiq, A Alwbari… - Breast cancer: basic …, 2018 - journals.sagepub.com
The immune system plays a major role in cancer surveillance. Harnessing its power to treat
many cancers is now a reality that has led to cures in hopeless situations where no other …
many cancers is now a reality that has led to cures in hopeless situations where no other …
Immunotherapy in breast cancer: an overview of current strategies and perspectives
V Debien, A De Caluwé, X Wang… - NPJ Breast …, 2023 - nature.com
Recent progress in immunobiology has led the way to successful host immunity
enhancement against breast cancer. In triple-negative breast cancer, the combination of …
enhancement against breast cancer. In triple-negative breast cancer, the combination of …
Immunotherapy for the treatment of breast cancer
B Ernst, KS Anderson - Current oncology reports, 2015 - Springer
Decades of research are now leading to therapeutics that target the molecular mechanisms
of the cancer-specific immune response. These therapeutics include tumor antigen …
of the cancer-specific immune response. These therapeutics include tumor antigen …
Checkpoint blockade strategies in the treatment of breast cancer: where we are and where we are heading
J Force, JHS Leal, HL McArthur - Current treatment options in oncology, 2019 - Springer
Opinion Statement Immunotherapy has become one of the greatest advances in medical
oncology over the last century; however, the optimal application for the treatment of breast …
oncology over the last century; however, the optimal application for the treatment of breast …
Immune targeting in breast cancer
A Cimino-Mathews, JB Foote, LA Emens - Oncology, 2015 - go.gale.com
The immune system is active in breast cancer, playing a dual role in tumor progression and
in immune surveillance. Infiltrating immune cells are both prognostic and predictive of …
in immune surveillance. Infiltrating immune cells are both prognostic and predictive of …
Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …
heterogeneity of this disease presents a big challenge in its therapeutic management …
Advances in personalized cancer immunotherapy
K Kakimi, T Karasaki, H Matsushita, T Sugie - Breast Cancer, 2017 - Springer
There are currently three major approaches to T cell-based cancer immunotherapy, namely,
active vaccination, adoptive cell transfer therapy and immune checkpoint blockade …
active vaccination, adoptive cell transfer therapy and immune checkpoint blockade …
Immune checkpoint inhibitors in triple negative breast cancer treatment: promising future prospects
R Thomas, G Al-Khadairi, J Decock - Frontiers in oncology, 2021 - frontiersin.org
Immunotherapy has emerged as the fifth pillar of cancer treatment alongside surgery,
radiotherapy, chemotherapy, and targeted therapy. Immune checkpoint inhibitors are the …
radiotherapy, chemotherapy, and targeted therapy. Immune checkpoint inhibitors are the …
Current landscape of immunotherapy in breast cancer: a review
S Adams, ME Gatti-Mays, K Kalinsky, LA Korde… - JAMA …, 2019 - jamanetwork.com
Importance There is tremendous interest in using immunotherapy to treat breast cancer, as
evidenced by the more than 290 clinical trials ongoing at the time of this narrative review …
evidenced by the more than 290 clinical trials ongoing at the time of this narrative review …