Directing induced pluripotent stem cell derived neural stem cell fate with a three-dimensional biomimetic hydrogel for spinal cord injury repair
L Fan, C Liu, X Chen, Y Zou, Z Zhou, C Lin… - … applied materials & …, 2018 - ACS Publications
Current treatment approaches for spinal cord injuries (SCIs) are mainly based on cellular
transplantation. Induced pluripotent stem cells (iPSCs) without supply constraints and ethical …
transplantation. Induced pluripotent stem cells (iPSCs) without supply constraints and ethical …
Dual-enzymatically cross-linked gelatin hydrogel enhances neural differentiation of human umbilical cord mesenchymal stem cells and functional recovery in …
M Yao, J Li, J Zhang, S Ma, L Wang, F Gao… - Journal of Materials …, 2021 - pubs.rsc.org
Recently, an advanced stem cell and tissue engineering approach has been recognized as
an emerging and fascinating strategy to promote neural repair in spinal cord injury (SCI) …
an emerging and fascinating strategy to promote neural repair in spinal cord injury (SCI) …
Promoting 3D neuronal differentiation in hydrogel for spinal cord regeneration
P Zhou, P Xu, J Guan, C Zhang, J Chang… - Colloids and Surfaces B …, 2020 - Elsevier
Spinal cord injury (SCI) affects millions of people worldwide, and results in the loss of
neurons and limited recovery of functions. Bone mesenchymal stem cells (BMSCs) and …
neurons and limited recovery of functions. Bone mesenchymal stem cells (BMSCs) and …
NSC-derived extracellular matrix-modified GelMA hydrogel fibrous scaffolds for spinal cord injury repair
Z Chen, L Wang, C Chen, J Sun, J Luo, W Cui… - NPG Asia …, 2022 - nature.com
Cell-derived extracellular matrix (ECM) has been applied in spinal cord injury (SCI)
regeneration because of its various biological functions. However, insufficient mechanical …
regeneration because of its various biological functions. However, insufficient mechanical …
Encapsulation of human spinal cord progenitor cells in hyaluronan-gelatin hydrogel for spinal cord injury treatment
C Kwokdinata, V Ramanujam, J Chen… - … Applied Materials & …, 2023 - ACS Publications
Transplanting human induced pluripotent stem cells (iPSCs)-derived spinal cord progenitor
cells (SCPCs) is a promising approach to treat spinal cord injuries. However, stem cell …
cells (SCPCs) is a promising approach to treat spinal cord injuries. However, stem cell …
An electroconductive hydrogel scaffold with injectability and biodegradability to manipulate neural stem cells for enhancing spinal cord injury repair
H Liu, Y Feng, S Che, L Guan, X Yang, Y Zhao… - …, 2022 - ACS Publications
Spinal cord injury (SCI) generally leads to long-term functional deficits and is difficult to
repair spontaneously. Many biological scaffold materials and stem cell treatment strategies …
repair spontaneously. Many biological scaffold materials and stem cell treatment strategies …
Regenerating the injured spinal cord at the chronic phase by engineered iPSCs‐derived 3D neuronal networks
L Wertheim, R Edri, Y Goldshmit, T Kagan… - Advanced …, 2022 - Wiley Online Library
Cell therapy using induced pluripotent stem cell‐derived neurons is considered a promising
approach to regenerate the injured spinal cord (SC). However, the scar formed at the …
approach to regenerate the injured spinal cord (SC). However, the scar formed at the …
Injectable nanoreinforced shape-memory hydrogel system for regenerating spinal cord tissue from traumatic injury
Traumatic injury in the central nervous system can lead to loss of functional neurons.
Transplantation of neural progenitors is a promising therapeutic strategy. However, infusion …
Transplantation of neural progenitors is a promising therapeutic strategy. However, infusion …
[HTML][HTML] Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation
Spinal cord injury (SCI) is one of the most challenging clinical issues. It is characterized by
the disruption of neural circuitry and connectivity, resulting in neurological disability. Adipose …
the disruption of neural circuitry and connectivity, resulting in neurological disability. Adipose …
Coaxial 3D printing of hierarchical structured hydrogel scaffolds for on-demand repair of spinal cord injury
Y Li, S Cheng, H Wen, L Xiao, Z Deng, J Huang… - Acta Biomaterialia, 2023 - Elsevier
After spinal cord injury (SCI), endogenous neural stem cells (NSCs) near the damaged site
are activated, but few NSCs migrate to the injury epicenter and differentiate into neurons …
are activated, but few NSCs migrate to the injury epicenter and differentiate into neurons …
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