Previous studies have demonstrated that pioglitazone, a peroxisome proliferator-activated
receptor gamma (PPARγ) agonist, inhibits ischemia-induced brain injury. The present study …

Previous studies have demonstrated that pioglitazone (Piog), a peroxisome proliferator-
activated receptor gamma (PPARγ) agonist, inhibits ischemia-induced brain injury. Piog has …

Traumatic brain injury (TBI) is still a major cause of concern for public health, and out of all
the trauma-related injuries, it makes the highest contribution to death and disability …

Following traumatic brain injury (TBI) there is significant neuropathology which includes
mitochondrial dysfunction, loss of cortical gray matter, microglial activation, and cognitive …

Peroxisome proliferator‐activated receptor gamma (PPAR‐γ) is a nuclear membrane‐
associated transcription factor that governs the expression of various inflammatory genes …

Our previous study showed that a single lipopolysaccharide (LPS) treatment to neonatal rats
could induce a long-lasting neuroinflammatory response and dopaminergic system injury …

Traumatic brain injury (TBI) is the major cause of high mortality and disability rates
worldwide. Pioglitazone is an activator of peroxisome proliferator-activated receptor-gamma …

The present study has planned to evaluate the neuroprotective activity of two novel
glitazones in a neuroinflammatory rat model. Two novel glitazones were selected from an in …

Background Gulf War (GW) Illness (GWI) is a debilitating condition with a complex
constellation of immune, endocrine and neurological symptoms, including cognitive …

Inflammatory and ischemic processes contribute to the development of secondary brain
damage after mechanical brain injury. Recent data suggest that thiazolidinediones (TZDs), a …