Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease

M Agrawal, DK Tripathi, S Saraf, S Saraf… - Journal of controlled …, 2017 - Elsevier
In this modern era, with the help of various advanced technologies, medical science has
overcome most of the health-related issues successfully. Though, some diseases still remain …

Liposomes for Targeted Delivery of Active Agents against Neurodegenerative Diseases (Alzheimer′ s Disease and Parkinson′ s Disease)

C Spuch, C Navarro - Journal of drug delivery, 2011 - Wiley Online Library
Neurodegenerative diseases, such as Alzheimer′ s disease and Parkinson′ s disease
represent a huge unmet medical need. The prevalence of both diseases is increasing, but …

Liposome based drug delivery as a potential treatment option for Alzheimer's disease

C Hernandez, S Shukla - Neural regeneration research, 2022 - journals.lww.com
Alzheimer's disease is a neurodegenerative condition leading to atrophy of the brain and
robbing nearly 5.8 million individuals in the United States age 65 and older of their cognitive …

Liposome delivery systems for the treatment of Alzheimer's disease

C Ross, M Taylor, N Fullwood… - International journal of …, 2018 - Taylor & Francis
Alzheimer's disease (AD) will affect around 115 million people worldwide by the year 2050.
It is associated with the accumulation of misfolded and aggregated proteins (β-amyloid and …

Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Liposomes for brain delivery

F Lai, AM Fadda, C Sinico - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Development of drug delivery systems for brain delivery is one of the most
challenging research topics in pharmaceutical areas, mainly due to the presence of the …

Novel concept of exosome-like liposomes for the treatment of Alzheimer's disease

M Fernandes, I Lopes, L Magalhães, MP Sárria… - Journal of Controlled …, 2021 - Elsevier
Exosomes are cell-derived vesicles that act as carriers for proteins and nucleic acids, with
therapeutic potential and high biocompatibility. We propose a new concept of exosome-like …

Liposomes and nanotechnology in drug development: focus on neurological targets

P Ramos-Cabrer, F Campos - International journal of …, 2013 - Taylor & Francis
Neurological diseases represent a medical, social, and economic problem of paramount
importance in developed countries. Although their etiology is generally known, developing …

Current insights on lipid nanocarrier-assisted drug delivery in the treatment of neurodegenerative diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - European journal of …, 2020 - Elsevier
The central nervous system (CNS) is vulnerable to pathologic processes that lead to the
development of neurodegenerative disorders like Alzheimer's, Parkinson's and Huntington's …

Multifunctional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in Alzheimer's disease mouse models

C Balducci, S Mancini, S Minniti… - Journal of …, 2014 - Soc Neuroscience
Alzheimer's disease is characterized by the accumulation and deposition of plaques of β-
amyloid (Aβ) peptide in the brain. Given its pivotal role, new therapies targeting Aβ are in …