Membranous nephropathy (MN) is the major cause of nephrotic syndrome with special
pathological features, caused by the formation of immune complexes in the space between …

Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage
caused by an autoimmune response. Immune complex deposition, thickness of glomerular …

Primary membranous nephropathy is a leading cause of adult nephrotic syndrome. The field
took a major step forward with the identification of phospholipase A2 receptor (PLA2R) as a …

Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome in
adults. In most cases, this autoimmune kidney disease is associated with autoantibodies …

The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Antibody-mediated autoimmune pathologies like membranous nephropathy are difficult to
model, particularly in the absence of local target antigen expression in model organisms …

Membranous nephropathy (MN) accounts for most cases of the nephrotic syndrome in
adults. Recently, studies on the underlying pathomechanisms led to the identification of the …

Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

The phospholipase A2 receptor 1 (PLA2R1) is the major autoantigen in patients suffering
from membranous nephropathy. To date, the lack of endogenous glomerular expression of …

Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …