[HTML][HTML] Biological functions of autophagy genes: a disease perspective
The lysosomal degradation pathway of autophagy plays a fundamental role in cellular,
tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy …
tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy …
[HTML][HTML] Epigenetic and post-translational modifications in autophagy: biological functions and therapeutic targets
F Shu, H Xiao, QN Li, XS Ren, ZG Liu, BW Hu… - … and Targeted Therapy, 2023 - nature.com
Autophagy is a conserved lysosomal degradation pathway where cellular components are
dynamically degraded and re-processed to maintain physical homeostasis. However, the …
dynamically degraded and re-processed to maintain physical homeostasis. However, the …
[HTML][HTML] Autophagy and human diseases
P Jiang, N Mizushima - Cell research, 2014 - nature.com
Autophagy is a major intracellular degradative process that delivers cytoplasmic materials to
the lysosome for degradation. Since the discovery of autophagy-related (Atg) genes in the …
the lysosome for degradation. Since the discovery of autophagy-related (Atg) genes in the …
[HTML][HTML] Emerging regulation and functions of autophagy
Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex
post-translational modulation of the Atg (autophagy-related) proteins adds additional entry …
post-translational modulation of the Atg (autophagy-related) proteins adds additional entry …
Regulation mechanisms and signaling pathways of autophagy
C He, DJ Klionsky - Annual review of genetics, 2009 - annualreviews.org
Autophagy is a process of self-degradation of cellular components in which double-
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …
[HTML][HTML] Autophagy: an essential degradation program for cellular homeostasis and life
Y Chun, J Kim - Cells, 2018 - mdpi.com
Autophagy is a lysosome-dependent cellular degradation program that responds to a variety
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …
[HTML][HTML] Autophagy: a lysosomal degradation pathway with a central role in health and disease
EL Eskelinen, P Saftig - Biochimica et Biophysica Acta (BBA)-Molecular …, 2009 - Elsevier
Autophagy delivers cytoplasmic material and organelles to lysosomes for degradation. The
formation of autophagosomes is controlled by a specific set of autophagy genes called atg …
formation of autophagosomes is controlled by a specific set of autophagy genes called atg …
Autophagy in disease: a double-edged sword with therapeutic potential
W Martinet, P Agostinis, B Vanhoecke… - Clinical …, 2009 - portlandpress.com
Autophagy is a catabolic trafficking pathway for bulk destruction and turnover of long-lived
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …
Autophagy—from molecular mechanisms to clinical relevance
M Lippai, Z Szatmári - Cell biology and toxicology, 2017 - Springer
Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …
from yeast to mammals. During this process, cooperating protein complexes are recruited in …
Endocytosis and autophagy: exploitation or cooperation?
Autophagy is a lysosome-mediated degradative system that is a highly conserved pathway
present in all eukaryotes. In all cells, double-membrane autophagosomes form and engulf …
present in all eukaryotes. In all cells, double-membrane autophagosomes form and engulf …