Asthma is a chronic inflammatory disorder of the airway. It is characterized by airway hyper-
reactivity, which can be attributed to the chronically inflamed airway. However, the molecular …

Interleukin (IL)-1β is a pleiotropic, pro-inflammatory cytokine that has been importantly
implicated in driving the inflammatory response and resultant changes in airway smooth …

Bronchial asthma is a chronic disorder characterized by airway inflammation, reversible
airway obstruction, and airway hyperresponsiveness. Eosinophils are believed to play …

BACKGROUND: Airflow in the lungs of patients with allergic asthma is impaired by
excessive mucus production and airway smooth muscle contractions. Elevated levels of the …

Asthma is a common, chronic inflammatory condition of the airways that leads to airway
hyperresponsiveness, reversible narrowing of the airways, and airway wall remodeling …

The management of asthma has changed significantly over the past decade reflecting the
recognition of a coincident chronic pulmonary inflammation. However, unlike other …

The degree of airway inflammation is directly related to asthma severity and associated
hyper-responsiveness. Airway inflammation is categorized into three types:(a) acute …

The present article will describe the potential role of airway smooth muscle (ASM) in
mediating both deleterious/beneficial effects of interferons (IFNs) in asthma. First described …

Asthma is increasingly being recognised as involving not only allergic inflammatory
mechanisms but also a variety of other cell types and cytokines. While the role of interferon-γ …

Decreased responsiveness to β-adrenergic receptor agonists is a characteristic feature of
human asthma. One explanation for this observation is that cytokines released in the …