Single cell transcriptome analysis of a cancer tissue can provide objective assessment of
subtype population or the activation of each of various microenvironment component cells …

Endometrial cancers are complex ecosystems composed of cells with distinct phenotypes,
genotypes, and epigenetic states. Current models do not adequately reflect oncogenic origin …

Endometrial cancer is the most common gynecologic malignancy in the United States but it
remains poorly understood at the molecular level. This investigation was conducted to …

The molecular events driving low-grade endometrioid endometrial carcinoma (LGEC)
development—like in many cancers—are incompletely understood. Hence, here we …

Background Integrative analysis of endometrioid endometrial carcinoma (EEC) using
multiple platforms has distinguished four molecular subgroups. However, the landscape of …

Women with endometriosis, a benign growth of endometrial tissue outside the uterine cavity,
are at increased risk of specific histotypes of epithelial ovarian cancer, such as ovarian …

Tumors are complex ecosystems harboring multiple cell types which might play a critical role
in tumor progression and treatment response. The endometrial epithelial cell identities and …

Endometrial cancer (EC) is a highly heterogeneous malignancy characterized by varied
pathology and prognoses, and the heterogeneity of its cancer cells and the tumor …

Endometriosis is a common, benign condition characterized by extensive heterogeneity in
lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual …

Background Endometrial cancer is the most common gynecologic malignancy in developed
countries and little is known about the underlying mechanism of stage and disease …