[HTML][HTML] Enteroviral 2B interacts with VDAC3 to regulate reactive oxygen species generation that is essential to viral replication
ML Cheng, CH Wu, KY Chien, CH Lai, GJ Li, YY Liu… - Viruses, 2022 - mdpi.com
Enterovirus (EV) 71 caused episodes of outbreaks in China and Southeast Asia during the
last few decades. We have previously reported that EV71 induces reactive oxygen species …
last few decades. We have previously reported that EV71 induces reactive oxygen species …
[HTML][HTML] Enterovirus 71 induces mitochondrial reactive oxygen species generation that is required for efficient replication
ML Cheng, SF Weng, CH Kuo, HY Ho - PLoS One, 2014 - journals.plos.org
Redox homeostasis is an important host factor determining the outcome of infectious
disease. Enterovirus 71 (EV71) infection has become an important endemic disease in …
disease. Enterovirus 71 (EV71) infection has become an important endemic disease in …
[HTML][HTML] Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection
D Dang, C Zhang, R Zhang, W Wu, S Chen, J Ren… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Enterovirus71 (EV71) is recognized as the main causative agent of severe hand,
foot and mouth disease (HFMD). However, the pathogenesis of EV71 infection has not been …
foot and mouth disease (HFMD). However, the pathogenesis of EV71 infection has not been …
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation
L You, J Chen, W Liu, Q Xiang, Z Luo, W Wang, W Xu… - Virulence, 2020 - Taylor & Francis
ABSTRACT Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD),
and even fatal neurological complications. However, the mechanisms underlying EV71 …
and even fatal neurological complications. However, the mechanisms underlying EV71 …
[HTML][HTML] Metabolic reprogramming of host cells in response to enteroviral infection
ML Cheng, KY Chien, CH Lai, GJ Li, JF Lin, HY Ho - Cells, 2020 - mdpi.com
Enterovirus 71 (EV71) infection is an endemic disease in Southeast Asia and China. We
have previously shown that EV71 virus causes functional changes in mitochondria. It is …
have previously shown that EV71 virus causes functional changes in mitochondria. It is …
Activation of PI3K/Akt pathway limits JNK-mediated apoptosis during EV71 infection
H Zhang, F Li, Z Pan, Z Wu, Y Wang, Y Cui - Virus research, 2014 - Elsevier
Apoptosis is frequently induced to inhibit virus replication during infection of Enterovirus 71
(EV71). On the contrary, anti-apoptotic pathway, such as PI3K/Akt pathway, is …
(EV71). On the contrary, anti-apoptotic pathway, such as PI3K/Akt pathway, is …
[HTML][HTML] Pathological features of enterovirus 71-associated brain and lung damage in mice based on quantitative proteomic analysis
Y Jin, D Li, T Sun, Y Du, Y Gao, R Ding, W Ji… - Frontiers in …, 2021 - frontiersin.org
The outbreaks of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD)
have emerged as an emergency of global health due to its association with fatal encephalitis …
have emerged as an emergency of global health due to its association with fatal encephalitis …
[HTML][HTML] Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication
X Yang, J Chen, Z Lu, S Huang, S Zhang… - Frontiers in …, 2022 - frontiersin.org
Enterovirus A71 (EV-A71) is a major pathogen that causes severe and fatal cases of hand-
foot-and-mouth disease (HFMD), which is an infectious disease that endangers children's …
foot-and-mouth disease (HFMD), which is an infectious disease that endangers children's …
[HTML][HTML] ATP1B3: a virus-induced host factor against EV71 replication by up-regulating the production of type-I interferons
Abstract Enterovirus 71 (EV71) infection can cause severe diseases, and is becoming
increasingly common in children. In the current study, we carried out yeast two-hybrid …
increasingly common in children. In the current study, we carried out yeast two-hybrid …
[HTML][HTML] Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses
Enterovirus 71 (EV71) is the major causative pathogen of hand, foot, and mouth disease
(HFMD). Its pathogenicity is not fully understood, but innate immune evasion is likely a key …
(HFMD). Its pathogenicity is not fully understood, but innate immune evasion is likely a key …