There has been increased interest in the development of RNA-based vaccines for protection
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …

mRNA vaccines elicit a potent immune response including antibodies and cytotoxic T cells.
mRNA vaccines are currently evaluated in clinical trials for cancer immunotherapy …

Nucleic acid-based therapies such as messenger RNA have the potential to revolutionize
modern medicine and enhance the performance of existing pharmaceuticals. The key …

The induction of a potent T cell response is essential for successful tumor immunotherapy
and protection against many infectious diseases. In the past few years, mRNA vaccines …

Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and
have shown promise for vaccine applications. Yet there are no published reports detailing …

Background Cancer remains a serious health concern worldwide, and different approaches
are being developed for its treatment. The strategy to use the immune system as an …

Abstract mRNA molecules hold tremendous potential as a tool for gene therapy of a wide
range of diseases. However, the main hurdle in implementation of mRNA for therapeutics …

RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

The efforts made to develop RNAi‐based therapies have led to productive research in the
field of infections in humans, such as hepatitis C virus (HCV), hepatitis B virus (HBV), human …

Messenger RNA (mRNA) vaccines constitute an emerging therapeutic method with the
advantages of high safety and efficiency as well as easy synthesis; thus, they have been …