Dual-Pseudorabies Viral Tracing for Spinal Tyrosine Hydroxylase Interneurons Involved in Segmental Micturition Reflex Circuitry in Spinal Cord Injured Rats

JH DeFinis, S Hou - Neurotrauma Reports, 2021 - liebertpub.com
Traumatic spinal cord injury (SCI) often leads to urinary dysfunction. Although an involuntary
micturition reflex can be established to elicit voiding with time, complications arise in the …

[图书][B] Elucidating Spinal Dopaminergic Mechanisms That Modulate the Recovered Micturition Reflex after Spinal Cord Injury

JH DeFinis - 2022 - search.proquest.com
Traumatic spinal cord injury (SCI) often results in lower urinary tract (LUT) dysfunction.
Although a spinal bladder reflex can be established over time, loss of supraspinal …

Spinal dopaminergic mechanisms regulating the micturition reflex in male rats with complete spinal cord injury

Y Qiao, ZD Brodnik, S Zhao, CT Trueblood… - Journal of …, 2021 - liebertpub.com
Traumatic spinal cord injury (SCI) often causes micturition dysfunction. We recently
discovered a low level of spinally-derived dopamine (DA) that regulates recovered bladder …

Delivery of the 5-HT2A Receptor Agonist, DOI, Enhances Activity of the Sphincter Muscle during the Micturition Reflex in Rats after Spinal Cord Injury

JH DeFinis, J Weinberger, S Hou - Biology, 2021 - mdpi.com
Simple Summary Spinal cord injury often disrupts connections between the brain and spinal
cord leading to a plethora of health complications, including bladder dysfunction. Spinal …

Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury

S Hou, DM Carson, D Wu, MC Klaw, JD Houlé… - Experimental …, 2016 - Elsevier
Dopamine (DA) neurons in the mammalian central nervous system are thought to be
restricted to the brain. DA-mediated regulation of urinary activity is considered to occur …

Deciphering spinal endogenous dopaminergic mechanisms that modulate micturition reflexes in rats with spinal cord injury

S Hou, JH DeFinis, SL Daugherty, C Tang… - Eneuro, 2021 - eneuro.org
Spinal neuronal mechanisms regulate recovered involuntary micturition after spinal cord
injury (SCI). It was recently discovered that dopamine (DA) is synthesized in the rat injured …

Locomotor exercise enhances supraspinal control of lower-urinary-tract activity to improve micturition function after contusive spinal-cord injury

L Deng, T Sui, DV Wang, S Hou, X Cao, K Peng, Z Xu… - Cells, 2022 - mdpi.com
The recovery of lower-urinary-tract activity is a top priority for patients with spinal-cord injury.
Historically, locomotor training improved micturition function in both patients with spinal cord …

Effect of spinal cord injury on urinary bladder spinal neural pathway: a retrograde transneuronal tracing study with pseudorabies virus

X Yu, L Xu, XD Zhang, FZ Cui - Urology, 2003 - Elsevier
OBJECTIVES: To determinate the effect of acute and chronic spinal cord injury (SCI)
resulting from thoracic cord transection on the urinary bladder spinal neural pathway …

Anatomical evidence for two spinal 'afferent–interneuron–efferent'reflex pathways involved in micturition in the rat: a 'pelvic nerve'reflex pathway and a 'sacrolumbar …

PL Vera, I Nadelhaft - Brain research, 2000 - Elsevier
We labeled interneurons in the L1–L2 and L6–S1 spinal cord segments of the rat that are
involved in bladder innervation using transneuronal retrograde transport of pseudorabies …

Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …