Pancreatic cancer

J Kleeff, M Korc, M Apte, C La Vecchia… - Nature reviews Disease …, 2016 - nature.com
Pancreatic cancer is a major cause of cancer-associated mortality, with a dismal overall
prognosis that has remained virtually unchanged for many decades. Currently, prevention or …

Therapeutic developments in pancreatic cancer: current and future perspectives

JP Neoptolemos, J Kleeff, P Michl, E Costello… - Nature reviews …, 2018 - nature.com
The overall 5-year survival for pancreatic cancer has changed little over the past few
decades, and pancreatic cancer is predicted to be the second leading cause of cancer …

Pancreatic cancer: a review of current treatment and novel therapies

HM Kolbeinsson, S Chandana, GP Wright… - Journal of Investigative …, 2023 - Taylor & Francis
Pancreatic cancer is one of the leading causes for cancer-related deaths in the United
States. Majority of patients present with unresectable or metastatic disease. For those that …

Pancreatic cancer: from bench to 5-year survival

J Kleeff, C Michalski, H Friess, MW Büchler - Pancreas, 2006 - journals.lww.com
Pancreatic ductal adenocarcinoma is one of the most aggressive human malignancies, with
an overall 5-year survival rate of less than 4%. On the molecular level, an increasing number …

Pancreatic cancer: current and future treatment strategies

K Pliarchopoulou, D Pectasides - Cancer treatment reviews, 2009 - Elsevier
Pancreatic cancer is a disease with a high mortality rate and short survival, as a result of the
high incidence of metastatic disease at diagnosis, the fulminant clinical course and the lack …

Advanced pancreatic carcinoma: current treatment and future challenges

A Stathis, MJ Moore - Nature reviews Clinical oncology, 2010 - nature.com
Pancreatic adenocarcinoma is the most lethal of the solid tumors and the fourth leading
cause of cancer-related death in North America. Most patients present with locally advanced …

[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

Pancreatic cancer: molecular pathogenesis and new therapeutic targets

HH Wong, NR Lemoine - Nature reviews Gastroenterology & …, 2009 - nature.com
Patients with pancreatic cancer normally present with advanced disease that is lethal and
notoriously difficult to treat. Survival has not improved dramatically despite routine use of …

[HTML][HTML] Pancreatic cancer: challenges and opportunities

H Zhu, T Li, Y Du, M Li - BMC medicine, 2018 - Springer
Pancreatic cancer is the fourth leading cause of cancer-related death in the United States,
with increasing incidence. The mortality rate of pancreatic cancer is rising rapidly, and is …

Treatment for pancreatic cancer: current therapy and continued progress

AC Lockhart, ML Rothenberg, JD Berlin - Gastroenterology, 2005 - Elsevier
In the last decade, continued efforts in pancreas cancer research have led to the
development of new, more effective therapies. Additionally, progress in understanding the …