The pathogenesis of systemic lupus erythematosus—an update
J Choi, ST Kim, J Craft - Current opinion in immunology, 2012 - Elsevier
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-
tolerance with activation of autoreactive T and B cells leading to production of pathogenic …
tolerance with activation of autoreactive T and B cells leading to production of pathogenic …
New insights into the immunopathogenesis of systemic lupus erythematosus
GC Tsokos, MS Lo, PC Reis, KE Sullivan - Nature Reviews …, 2016 - nature.com
The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …
Emerging and critical issues in the pathogenesis of lupus
M Gatto, M Zen, A Ghirardello, S Bettio, N Bassi… - Autoimmunity …, 2013 - Elsevier
Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease,
encompassing either mild or severe manifestations. SLE was originally labeled as being an …
encompassing either mild or severe manifestations. SLE was originally labeled as being an …
Pathogenesis of human systemic lupus erythematosus: a cellular perspective
VR Moulton, A Suarez-Fueyo, E Meidan, H Li… - Trends in molecular …, 2017 - cell.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple
organs. A complex interaction of genetics, environment, and hormones leads to immune …
organs. A complex interaction of genetics, environment, and hormones leads to immune …
Monocyte and macrophage abnormalities in systemic lupus erythematosus
Y Li, PY Lee, WH Reeves - Archivum immunologiae et therapiae …, 2010 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with profound effects
on multiple organ systems. In patients with SLE, the immune system is subverted to target …
on multiple organ systems. In patients with SLE, the immune system is subverted to target …
The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus
LS Davis, J Hutcheson, C Mohan - Journal of interferon & cytokine …, 2011 - liebertpub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized
by a defect in immune tolerance and exacerbated by both the innate and adaptive arms of …
by a defect in immune tolerance and exacerbated by both the innate and adaptive arms of …
Pathogenic inflammation and its therapeutic targeting in systemic lupus erythematosus
Systemic lupus erythematosus (SLE, lupus) is a highly complex and heterogeneous
autoimmune disease that most often afflicts women in their child-bearing years. It is …
autoimmune disease that most often afflicts women in their child-bearing years. It is …
T-and B-cell abnormalities in systemic lupus erythematosus
G Nagy, A Koncz, A Perl - Critical Reviews™ in Immunology, 2005 - dl.begellhouse.com
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the
production of antinuclear autoantibodies and clinical involvement in multiple organ systems …
production of antinuclear autoantibodies and clinical involvement in multiple organ systems …
Taming lupus—a new understanding of pathogenesis is leading to clinical advances
Z Liu, A Davidson - Nature medicine, 2012 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the
loss of tolerance to nuclear self antigens, the production of pathogenic autoantibodies and …
loss of tolerance to nuclear self antigens, the production of pathogenic autoantibodies and …
The pathology of T cells in systemic lupus erythematosus
A Mak, NY Kow - Journal of immunology research, 2014 - Wiley Online Library
Systemic lupus erythematosus (SLE) is characterized by the production of a wide array of
autoantibodies. Thus, the condition was traditionally classified as a “B‐cell disease” …
autoantibodies. Thus, the condition was traditionally classified as a “B‐cell disease” …