We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …

Despite their known importance in clinical medicine, differences based on sex and gender
are among the least studied factors affecting cancer susceptibility, progression, survival, and …

The incidence of many types of cancer arising in organs with non-reproductive functions is
significantly higher in male populations than in female populations, with associated …

Sex is a key biological factor affecting the development of many cancer types. There are
considerable differences between male and female subpopulations in terms of cancer …

The incidence and mortality of various cancers are associated with sex-specific disparities.
Sex differences in cancer epidemiology are one of the most significant findings. Men are …

An individual's sex has been long recognized as a key factor affecting cancer incidence,
prognosis, and treatment responses. However, the molecular basis for sex disparities in …

Sex differences in cellular and systems biology have been evolutionarily selected to
optimize reproductive success in all species with little (sperm) and big (ova) gamete …

In hormone-dependent organs, sex hormones and dysregulated hormone signaling have
well-documented roles in cancers of the breast and female reproductive organs including …

Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

The influence of biological sex differences on human health and disease, while being
increasingly recognized, has long been underappreciated and underexplored. While …