Sex differences in cancer mechanisms
JB Rubin, JS Lagas, L Broestl, J Sponagel… - Biology of sex …, 2020 - Springer
We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …
single histological subtype. With the current emphasis on developing personalized …
Genome-wide sex and gender differences in cancer
CM Lopes-Ramos, J Quackenbush… - Frontiers in oncology, 2020 - frontiersin.org
Despite their known importance in clinical medicine, differences based on sex and gender
are among the least studied factors affecting cancer susceptibility, progression, survival, and …
are among the least studied factors affecting cancer susceptibility, progression, survival, and …
Sexual dimorphism in cancer
A Clocchiatti, E Cora, Y Zhang, GP Dotto - Nature Reviews Cancer, 2016 - nature.com
The incidence of many types of cancer arising in organs with non-reproductive functions is
significantly higher in male populations than in female populations, with associated …
significantly higher in male populations than in female populations, with associated …
[HTML][HTML] Sex disparities in cancer
Y Zhu, X Shao, X Wang, L Liu, H Liang - Cancer letters, 2019 - Elsevier
Sex is a key biological factor affecting the development of many cancer types. There are
considerable differences between male and female subpopulations in terms of cancer …
considerable differences between male and female subpopulations in terms of cancer …
[HTML][HTML] Sex differences in cancer: epidemiology, genetics and therapy
HI Kim, H Lim, A Moon - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
The incidence and mortality of various cancers are associated with sex-specific disparities.
Sex differences in cancer epidemiology are one of the most significant findings. Men are …
Sex differences in cancer epidemiology are one of the most significant findings. Men are …
Comprehensive characterization of molecular differences in cancer between male and female patients
An individual's sex has been long recognized as a key factor affecting cancer incidence,
prognosis, and treatment responses. However, the molecular basis for sex disparities in …
prognosis, and treatment responses. However, the molecular basis for sex disparities in …
[HTML][HTML] The spectrum of sex differences in cancer
JB Rubin - Trends in cancer, 2022 - cell.com
Sex differences in cellular and systems biology have been evolutionarily selected to
optimize reproductive success in all species with little (sperm) and big (ova) gamete …
optimize reproductive success in all species with little (sperm) and big (ova) gamete …
The sex bias of cancer
AR Costa, ML de Oliveira, I Cruz, I Gonçalves… - Trends in Endocrinology …, 2020 - cell.com
In hormone-dependent organs, sex hormones and dysregulated hormone signaling have
well-documented roles in cancers of the breast and female reproductive organs including …
well-documented roles in cancers of the breast and female reproductive organs including …
Sex disparities matter in cancer development and therapy
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …
molecular and genomic therapies. Currently, whether patients with non-reproductive …
Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma
SC Massey, P Whitmire, TE Doyle, JE Ippolito… - Cancer letters, 2021 - Elsevier
The influence of biological sex differences on human health and disease, while being
increasingly recognized, has long been underappreciated and underexplored. While …
increasingly recognized, has long been underappreciated and underexplored. While …