Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

MS Hakim, AT Aman - Viruses, 2022 - mdpi.com
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by
the sudden onset of symptoms, including fever, rash, myalgia, and headache. In some …

Chikungunya virus: recent advances in epidemiology, host pathogen interaction and vaccine strategies

F Deeba, A Islam, SN Kazim, IH Naqvi… - FEMS Pathogens …, 2016 - academic.oup.com
The Chikungunya virus is a re-emerging alphavirus that belongs to the family Togaviridae.
The symptoms include fever, rashes, nausea and joint pain that may last for months. The …

Chikungunya virus vaccines: platforms, progress, and challenges

VR DeFilippis - Chikungunya Virus, 2019 - Springer
Chikungunya is a clinically and economically important arbovirus that has spread globally in
the twenty-first century. While uncommonly fatal, infection with the virus can lead to …

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen

FJ Burt, W Chen, JJ Miner, DJ Lenschow… - The Lancet Infectious …, 2017 - thelancet.com
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …

Understanding molecular pathogenesis with chikungunya virus research tools

G Carissimo, LFP Ng - Chikungunya Virus, 2019 - Springer
Since its re-emergence in 2006, Chikungunya has been a major health concern in endemic
areas. Transmitted by Aedes mosquitoes to mammalian hosts, Chikungunya leads to …

The biology of chikungunya: a brief review of what we still do not know

N Pardigon - Pathologie Biologie, 2009 - Elsevier
Responsible for a massive outbreak in the Indian Ocean in 2005–2006, the chikungunya
virus is also reemerging in India where it has already infected over a million persons …

[HTML][HTML] Immuno-biology of Chikungunya and implications for disease intervention

YW Kam, EKS Ong, L Rénia, JC Tong, LFP Ng - Microbes and infection, 2009 - Elsevier
The re-emergence of Chikungunya fever, an old tropical infectious disease with new
characteristics represents a major public health problem with severe social and economic …

Chikungunya, a paradigm of neglected tropical disease that emerged to be a new health global risk

V Rougeron, IC Sam, M Caron, D Nkoghe… - Journal of clinical …, 2015 - Elsevier
Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family that causes chronic
and incapacitating arthralgia in human populations. Since its discovery in 1952, CHIKV was …

How Chikungunya virus virology affects its epidemiology and transmission: implications for influencing public health

AM Powers - The Journal of infectious diseases, 2016 - academic.oup.com
Chikungunya virus has been causing a series of ongoing epidemics around the globe for
the past 12 years. During that time, estimates indicate that> 4 million cases occurred …

A review on chikungunya virus epidemiology, pathogenesis and current vaccine development

TYV de Lima Cavalcanti, MR Pereira, SO de Paula… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …