[HTML][HTML] Fuxin Granules ameliorate diabetic nephropathy in db/db mice through TGF-β1/Smad and VEGF/VEGFR2 signaling pathways
W Zheng, C Qian, F Xu, P Cheng, C Yang, X Li… - Biomedicine & …, 2021 - Elsevier
Diabetic nephropathy (DN) is a common disease, and patients often do not have satisfactory
treatments. We investigated therapeutic effects of Fuxin Granules (FX) on DN and potential …
treatments. We investigated therapeutic effects of Fuxin Granules (FX) on DN and potential …
[HTML][HTML] Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes
J Chen, W Cui, Q Zhang, Y Jia, Y Sun… - American journal of …, 2015 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is one of the most serious microvascular complications of
diabetes and may lead to end-stage renal disease (ESRD) and chronic renal failure. The …
diabetes and may lead to end-stage renal disease (ESRD) and chronic renal failure. The …
Low molecular weight fucoidan ameliorates the inflammation and glomerular filtration function of diabetic nephropathy
Y Xu, Q Zhang, D Luo, J Wang, D Duan - Journal of Applied Phycology, 2017 - Springer
Diabetic nephropathy (DN) is a type of serious microangiopathy that is caused by diabetes
mellitus (DM). It is the most common cause of chronic renal failure and end-stage renal …
mellitus (DM). It is the most common cause of chronic renal failure and end-stage renal …
[HTML][HTML] Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro
Y Wang, M Nie, Y Lu, R Wang, J Li… - International …, 2015 - spandidos-publications.com
Fucoidan, an extract of the seaweed, Fucus vesiculosus, has been widely investigated for its
antioxidant effects. However, to date and to the best of our knowledge, pathological studies …
antioxidant effects. However, to date and to the best of our knowledge, pathological studies …
[HTML][HTML] FGF23C-tail improves diabetic nephropathy by attenuating renal fibrosis and inflammation
X Zhang, K Guo, F Xia, X Zhao, Z Huang, J Niu - BMC biotechnology, 2018 - Springer
Background High level of serum fibroblast growth factor 23 (FGF23) is implicated in the
development and progression of diabetic nephropathy (DN), making it a crucial factor in the …
development and progression of diabetic nephropathy (DN), making it a crucial factor in the …
[HTML][HTML] Oligo-fucoidan improves diabetes-induced renal fibrosis via activation of Sirt-1, GLP-1R, and Nrf2/HO-1: an in vitro and in vivo study
WC Yu, RY Huang, TC Chou - Nutrients, 2020 - mdpi.com
Fucoidan extracted from brown algae has multiple beneficial functions. In this study, we
investigated the effects of low-molecular-weight fucoidan (oligo-FO) on renal fibrosis under …
investigated the effects of low-molecular-weight fucoidan (oligo-FO) on renal fibrosis under …
Inhibition of core fucosylation limits progression of diabetic kidney disease
M Fang, L Kang, X Wang, X Guo, W Wang, B Qin… - Biochemical and …, 2019 - Elsevier
Background FUT8-mediated core fucosylation, which transfers a fucose residue from GDP-
fucose to core-GlcNAc of the N-linked type glycoproteins, is crucial for signaling receptors …
fucose to core-GlcNAc of the N-linked type glycoproteins, is crucial for signaling receptors …
Low molecular weight fucoidan can inhibit the fibrosis of diabetic kidneys by regulating the kidney lipid metabolism
Y Wang, Y Sun, F Shao, B Zhang… - Journal of Diabetes …, 2021 - Wiley Online Library
In this study, a diabetic kidney disease model was established by placing the test rats on a
high‐sugar/high‐fat diet combined with streptozotocin induction. Histopathological …
high‐sugar/high‐fat diet combined with streptozotocin induction. Histopathological …
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model
Abstract Fufang Xueshuantong Capsule (FXST) can reduce urinary albumin and whole
blood viscosity in early diabetic nephropathy (DN) patients. This research aimed to …
blood viscosity in early diabetic nephropathy (DN) patients. This research aimed to …
Fucoidan mitigated diabetic nephropathy through the downregulation of PKC and modulation of NF‐κB signaling pathway: in vitro and in vivo investigations
J Xu, Y Wang, Z Wang, L Guo, X Li - Phytotherapy Research, 2021 - Wiley Online Library
The persistence of hyperglycemia and oxidative stress in diabetic patients ultimately leads to
diabetic nephropathy (DN). In this study, we investigated the effect of sulfated …
diabetic nephropathy (DN). In this study, we investigated the effect of sulfated …
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