Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host
T Bouklas, L Alonso-Crisóstomo, T Székely Jr… - PLoS …, 2017 - journals.plos.org
Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …
One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation
S Brunke, K Seider, D Fischer, ID Jacobsen… - PLoS …, 2014 - journals.plos.org
Candida glabrata is one of the most common causes of candidemia, a life-threatening,
systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major …
systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major …
Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts
VKA Silva, S Bhattacharya, NK Oliveira, AG Savitt… - MBio, 2022 - Am Soc Microbiol
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …
Ploidy variation and spontaneous haploid-diploid switching of Candida glabrata clinical isolates
Q Zheng, J Liu, J Qin, B Wang, J Bing, H Du, M Li, F Yu… - Msphere, 2022 - Am Soc Microbiol
The human fungal pathogen Candida glabrata is phylogenetically closely related to
Saccharomyces cerevisiae, a model eukaryotic organism. Unlike S. cerevisiae, which has …
Saccharomyces cerevisiae, a model eukaryotic organism. Unlike S. cerevisiae, which has …
Replicative aging in pathogenic fungi
S Bhattacharya, T Bouklas, BC Fries - Journal of Fungi, 2020 - mdpi.com
Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
[PDF][PDF] Intracellular survival of Candida glabrata in macrophages: immune evasion and persistence
L Kasper, K Seider, B Hube - FEMS Yeast Research, 2015 - academic.oup.com
Candida glabrata is a successful human opportunistic pathogen which causes superficial
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
The birth of a deadly yeast: tracing the evolutionary emergence of virulence traits in Candida glabrata
T Gabaldón, L Carreté - FEMS yeast research, 2016 - academic.oup.com
The yeast Candida glabrata is an opportunistic human fungal pathogen whose incidence
has increased in the last two decades. Despite its name, this yeast is only distantly related to …
has increased in the last two decades. Despite its name, this yeast is only distantly related to …
Patterns of genomic variation in the opportunistic pathogen Candida glabrata suggest the existence of mating and a secondary association with humans
L Carreté, E Ksiezopolska, C Pegueroles… - Current Biology, 2018 - cell.com
Candida glabrata is an opportunistic fungal pathogen that ranks as the second most
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages
K Seider, F Gerwien, L Kasper, S Allert, S Brunke… - Eukaryotic …, 2014 - Am Soc Microbiol
Candida glabrata is both a human fungal commensal and an opportunistic pathogen which
can withstand activities of the immune system. For example, C. glabrata can survive …
can withstand activities of the immune system. For example, C. glabrata can survive …
Functional Genomic Analysis of Candida glabrata-Macrophage Interaction: Role of Chromatin Remodeling in Virulence
MN Rai, S Balusu, N Gorityala, L Dandu, R Kaur - 2012 - journals.plos.org
Fungal septicemia is an increasingly common complication of immunocompromised patients
worldwide. Candida species are the leading cause of invasive mycoses with Candida …
worldwide. Candida species are the leading cause of invasive mycoses with Candida …
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