Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host
T Bouklas, L Alonso-Crisóstomo, T Székely Jr… - PLoS …, 2017 - journals.plos.org
Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …
One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation
S Brunke, K Seider, D Fischer, ID Jacobsen… - PLoS …, 2014 - journals.plos.org
Candida glabrata is one of the most common causes of candidemia, a life-threatening,
systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major …
systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major …
Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …
Ploidy variation and spontaneous haploid-diploid switching of Candida glabrata clinical isolates
Q Zheng, J Liu, J Qin, B Wang, J Bing, H Du, M Li, F Yu… - Msphere, 2022 - Am Soc Microbiol
The human fungal pathogen Candida glabrata is phylogenetically closely related to
Saccharomyces cerevisiae, a model eukaryotic organism. Unlike S. cerevisiae, which has …
Saccharomyces cerevisiae, a model eukaryotic organism. Unlike S. cerevisiae, which has …
Replicative aging in pathogenic fungi
S Bhattacharya, T Bouklas, BC Fries - Journal of Fungi, 2020 - mdpi.com
Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
The birth of a deadly yeast: tracing the evolutionary emergence of virulence traits in Candida glabrata
T Gabaldón, L Carreté - FEMS yeast research, 2016 - academic.oup.com
The yeast Candida glabrata is an opportunistic human fungal pathogen whose incidence
has increased in the last two decades. Despite its name, this yeast is only distantly related to …
has increased in the last two decades. Despite its name, this yeast is only distantly related to …
[PDF][PDF] Intracellular survival of Candida glabrata in macrophages: immune evasion and persistence
Candida glabrata is a successful human opportunistic pathogen which causes superficial
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
Patterns of genomic variation in the opportunistic pathogen Candida glabrata suggest the existence of mating and a secondary association with humans
Candida glabrata is an opportunistic fungal pathogen that ranks as the second most
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
common cause of systemic candidiasis. Despite its genus name, this yeast is more closely …
Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages
Candida glabrata is both a human fungal commensal and an opportunistic pathogen which
can withstand activities of the immune system. For example, C. glabrata can survive …
can withstand activities of the immune system. For example, C. glabrata can survive …
From Saccharomyces cerevisiae to Candida glabrata in a few easy steps: important adaptations for an opportunistic pathogen
A Roetzer, T Gabaldón, C Schüller - FEMS microbiology letters, 2011 - academic.oup.com
The opportunistic human fungal pathogen Candida glabrata is closely related to
Saccharomyces cerevisiae, yet it has evolved to survive within mammalian hosts. Which …
Saccharomyces cerevisiae, yet it has evolved to survive within mammalian hosts. Which …
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