Human calcitonin release is promoted by elevated extracellular Ca2+ (Ca2+ o)
concentration acting, at least in part, via the calcium-sensing receptor (CaSR). The CaSR is …

Current rat calcitonin immunoassays use human calcitonin antisera, and suffer from poor
sensitivity, long incubation periods, nonspecific interferences, and unreliability. The …

Calcitonin (CT) and related peptides, such as CT gene-related peptide and salmon CT (sCT)-
like peptide, are present in the rat nervous system and the pituitary gland, and sCT markedly …

The calcium-sensing receptor (CaSR)-specific allosteric modulator cinacalcet has
revolutionized the treatment of secondary hyperparathyroidism in patients with chronic …

Calcitonin (CT) is a peptide hormone that is secreted by the parafollicular cells of the thyroid
in response to elevated serum calcium levels. It acts to reduce serum calcium by inhibiting …

Calcium-sensing receptors (CaSRs) are class CG protein-coupled receptors that respond to
physiological activators, including extracellular Ca2+ (Cao2+) and l-amino acids as well as …

Background The calcium sensing receptor (CaSR) regulates serum calcium by suppressing
secretion of parathyroid hormone; it also regulates renal tubular calcium excretion …

The calcitonin receptor has been proposed to function as an extracellular Ca 2+
concentration ([Ca 2+] o) sensor (Stroop, SD, Thompson, DL, Kuestner, RE, and Moore, EE …

Background Calcitonin (CT) is a polypeptide hormone secreted from C‐cells of the thyroid
gland in response to hypercalcemia. The physiological contribution of CT to calcium …

Calcitonin (CT) secretion by parafollicular cells of the thyroid (C cells) is regulated by small
changes in the concentration of extracellular calcium ([Ca2+] e). Elevation of [Ca2+] e elicits …