Idiopathic pulmonary fibrosis (IPF) is a chronic and irreversible lung disease with limited
therapeutic strategies. Lycorine (LYC), an alkaloid isolated from Amaryllidaceae family …

Increasing evidence demonstrates that pyroptosis, pro-inflammatory programmed cell death,
is linked to acute lung injury (ALI). Dihydromyricetin (DHM) has been reported to exert anti …

Background Honokiol (HKL) has been reported to ameliorate lipopolysaccharide (LPS)-
induced acute lung injury (ALI). However, its potential mechanism of its protective effects …

Idiopathic Pulmonary fibrosis (IPF) is diagnosed as a life-threatening, progressive and
incurable lung disease characterized by accumulation of extracellular matrix and …

Geraniol (GOH), a special type of acyclic monoterpene alcohol, has been widely used to
treat many diseases associated with inflammation and apoptosis. Acute lung injury (ALI) is a …

Ligustrazine (Tetramethylpyrazine, TMP) is an active substance extracted from the
Umbelliferae plant Ligusticum chuanxiong. It has been proven to have antioxidant and …

Silybin is one of the main flavonoids produced by milk thistle, which has been used in the
treatment of liver diseases. In this study, we examined the protective effects and possible …

Abstract Background Xuanfei Baidu Formula (XBF) is an effective traditional Chinese
medicine (TCM) remedy for treating coronavirus disease 2019 (COVID-19) in China. This …

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common clinical
syndrome of diffuse lung inflammation with high mortality rates and limited therapeutic …

Among the cellular response mechanisms, the nuclear factor erythroid-2 related factor 2
(Nrf2) pathway is considered a survival pathway that alleviates oxidative injury, while both …