Diet influences community dynamics following vaginal group B Streptococcus colonization

CJ Megli, AE DePuyt, JP Goff, SK Munyoki… - Microbiology …, 2024 - Am Soc Microbiol
The vaginal microbiota plays a pivotal role in reproductive, sexual, and perinatal health and
disease. Unlike the well-established connections between diet, metabolism, and the …

[HTML][HTML] The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus

A Vrbanac, AM Riestra, A Coady, R Knight, V Nizet… - BMC microbiology, 2018 - Springer
Background Composition of the vaginal microbiota has significant influence on female
urogenital health and control of infectious disease. Murine models are widely utilized to …

[HTML][HTML] Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

ME Mejia, V Mercado-Evans, JJ Zulk… - npj Biofilms and …, 2023 - nature.com
Vaginal microbial composition is associated with differential risk of urogenital infection.
Although Lactobacillus spp. are thought to confer protection against infection, the lack of in …

Human Milk Oligosaccharides Reduce Murine Group B Streptococcus Vaginal Colonization with Minimal Impact on the Vaginal Microbiota

ME Mejia, S Ottinger, A Vrbanac, P Babu, JJ Zulk… - Msphere, 2022 - Am Soc Microbiol
ABSTRACT Group B Streptococcus (GBS) colonizes the vaginal mucosa of a significant
percentage of healthy women and is a leading cause of neonatal bacterial infections …

The human vaginal microbiota: from clinical medicine to models to mechanisms

S Ottinger, CM Robertson, H Branthoover… - Current Opinion in …, 2024 - Elsevier
Highlights●Live microbial biotherapeutics are emerging treatments for bacterial
vaginosis.●Metagenomics reveal vaginal subspecies are differentially associated with …

[HTML][HTML] A human microbiota-associated murine model for assessing the impact of the vaginal microbiota on pregnancy outcomes

AA Wolfarth, TM Smith, D VanInsberghe… - Frontiers in Cellular …, 2020 - frontiersin.org
Disease states are often linked to large scale changes in microbial community structure that
obscure the contributions of individual microbes to disease. Establishing a mechanistic …

[HTML][HTML] Alterations of the vaginal microbiome in healthy pregnant women positive for group B Streptococcus colonization during the third trimester

S Shabayek, AM Abdellah, M Salah, M Ramadan… - BMC microbiology, 2022 - Springer
Background Streptococcus agalactiae or group B Streptococcus (GBS) asymptomatically
colonizes the genitourinary tracts of up to 30% of pregnant women. Globally, GBS is an …

Interrelated effects of zinc deficiency and the microbiome on group B streptococcal vaginal colonization

LR Burcham, ZM Burcham, MS Akbari, JL Metcalf… - Msphere, 2022 - Am Soc Microbiol
ABSTRACT Group B Streptococcus (GBS) in the vaginal tract is a risk factor for preterm birth
and adverse pregnancy outcomes. GBS colonization is also transient in nature, which likely …

A murine model of group B Streptococcus vaginal colonization

KA Patras, KS Doran - JoVE (Journal of Visualized Experiments), 2016 - jove.com
Streptococcus agalactiae (group B Streptococcus, GBS), is a Gram-positive, asymptomatic
colonizer of the human gastrointestinal tract and vaginal tract of 10-30% of adults. In immune …

[HTML][HTML] Human vaginal microbiota colonization is regulated by female sex hormones in a mouse model

N Rahman, MF Mian, A Nazli… - Frontiers in Cellular and …, 2023 - frontiersin.org
Introduction Clinically, a Lactobacillus rich vaginal microbiota (VMB) is considered optimal
for reproductive outcomes, while a VMB populated by anaerobes is associated with …