Fabry disease is an X-linked inherited condition due to the absence or reduction of α-
galactosidase activity in lysosomes, that results in accumulation of globotriaosylceramide …

Fabry disease is an X-linked metabolic storage disorder due to the deficiency of lysosomal α-
galactosidase A, and the subsequent accumulation of glycosphingolipids, primarily …

Background Fabry disease is a rare X‐linked disorder caused by deficient activity of the
lysosomal enzyme α‐galactosidase A. Progressive accumulation of the substrate …

Background Fabry disease is a rare X‐linked disorder caused by deficient activity of the
lysosomal enzyme α‐galactosidase A. Progressive accumulation of the substrate …

Abstract Background In Fabry disease (α-galactosidase A deficiency) accumulation of
Globotriaosylceramide (Gb3) leads to progressive organ failure and premature death. The …

Gastrointestinal symptoms are often an early and prominent manifestation of Fabry disease,
an X-linked inborn error of metabolism caused by the deficient activity of the lysosomal …

Fabry disease: Diagnosis and treatment. Fabry disease is an X-linked lysosomal storage
disorder that results from a deficiency of the enzyme α-galactosidase A (α-Gal A). The lack of …

Fabry disease is a rare, X-linked inborn error of glycosphingolipid catabolism caused by a
deficiency in the activity of the lysosomal enzyme, α-galactosidase A. In affected patients, the …

Fabry disease (FD) is an X‐linked disease in which mutations of the GLA gene result in a
deficiency of the enzyme α‐galactosidase A and subsequent progressive, intralysosomal …

Fabry disease is an X-linked lysosomal storage disorder caused by mutations in the GLA
gene leading to deficient α-galactosidase A activity, glycosphingolipid accumulation, and life …