The evolving landscape of neuroendocrine tumors

EK Bergsland - Seminars in Oncology, 2013 - Elsevier
Neuroendocrine tumors (NET) encompass a heterogeneous group of tumors demonstrating
varied clinical behavior. The field has recently witnessed several important developments …

Molecular pathogenesis of neuroendocrine tumors: implications for current and future therapeutic approaches

K Oberg, O Casanovas, JP Castaño, D Chung… - Clinical Cancer …, 2013 - AACR
The treatment landscape and biologic understanding of neuroendocrine tumors (NET) has
shifted dramatically in recent years. Recent studies have shown that somatostatin analogues …

Novel therapeutic agents for the treatment of gastroenteropancreatic neuroendocrine tumors

ME Pavel, B Wiedenmann - Hormone and metabolic research, 2011 - thieme-connect.com
Neuroendocrine tumors (NET) are frequently diagnosed late and not amenable to curative
surgery due to metastatic disease to the liver and lymph nodes. The disease is complex and …

Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies

F Barbieri, M Albertelli, F Grillo, A Mohamed… - Drug discovery today, 2014 - Elsevier
Highlights•Novel therapeutic options are crucially needed for relatively rare but deadly
NETs.•Somatostatin analogs control tumor growth and symptoms in selected …

[HTML][HTML] Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors

BG Naraev, JR Strosberg, TR Halfdanarson - Oncology, 2012 - karger.com
Although neuroendocrine tumors (NET) are a relatively rare malignancy, the reported
incidence is increasing, and some of the current treatment options are limited in their …

New strategies for advanced neuroendocrine tumors in the era of targeted therapy

M Dong, AT Phan, JC Yao - Clinical Cancer Research, 2012 - AACR
Low-to intermediate-grade neuroendocrine tumor (NET) constitutes a group of indolent
malignancies that share the capacity for secreting hormones and neuroamines. Until …

Therapy of patients with neuroendocrine neoplasia—evidence-based approaches and new horizons

RA Bundschuh, B Habacha, S Lütje… - Journal of Clinical …, 2019 - mdpi.com
Neuroendocrine tumors (NETs) show low but increasing incidence and originate in multiple
organs, including the pancreas, midgut, caecum, rectum, appendix, colon, and lungs. Due to …

New treatment options for patients with advanced neuroendocrine tumors

JA Chan, MH Kulke - Current treatment options in oncology, 2011 - Springer
Opinion statement Well-to moderately differentiated neuroendocrine tumors (NET) are a
heterogeneous group of malignancies for which a range of therapeutic options have been …

Current clinical trials of targeted agents for well-differentiated neuroendocrine tumors

N Raj, D Reidy-Lagunes - Pancreas, 2014 - journals.lww.com
Neuroendocrine tumors (NETs) are a group of tumors originating in various locations,
including the gastrointestinal tract, lung, and pancreas. Clinical trial design and disease …

Gastroenteropancreatic neuroendocrine tumors

M Cives, JR Strosberg - CA: a cancer journal for clinicians, 2018 - Wiley Online Library
Neuroendocrine tumors (NETs) are heterogeneous malignancies arising from the diffuse
neuroendocrine system. They frequently originate in the gastroenteropancreatic (GEP) tract …