In this study we explore the spatio‐temporal trajectory and clinical relevance of
microstructural white matter changes within and beyond subcortical stroke lesions detected …

BACKGROUND AND PURPOSE: We studied the evolution of brain water compartments
during the early stage of ischemic stroke. METHODS: Diffusion-weighted imaging was …

Leukoaraiosis is a neuroimaging marker of small-vessel disease that is characterized by
high signal intensity on fluid-attenuated inversion recovery MRI. There is increasing …

Background The progression of FLAIR white matter hyperintensities (WMHs) on MRI heralds
vascular-mediated cognitive decline. Even before FLAIR WMH progression, adjacent normal …

High resolution structural magnetic resonance imaging (MRI) sequences reproducibly
identify even small stroke lesions, but relating the size of lesions to clinical impairment and …

Background Non-infarct zone white matter wallerian degeneration is well-documented in
large volume territorial infarctions. However to what extent these abnormalities exist in small …

Background and Purpose: The immediate decrease of the apparent diffusion coefficient
(ADC) is the main characteristic change of water diffusion in acute ischemic stroke. There is …

Purpose: Temporal evolution of the water apparent diffusion coefficients (ADC) parallel
(ADC∥) and perpendicular (ADC⊥) to the human white matter tract following ischemia has …

Background and Purpose—The purpose of this study was to evaluate changes in fractional
anisotropy (FA), as measured by diffusion tensor imaging, of white matter (WM) infarction …

ABSTRACT BACKGROUND AND PURPOSE Degeneration of gray matter and subcortical
structures after ischemic stroke has been well described. However, little is known about …