Candida albicans, an opportunistic fungus, and Staphylococcus aureus, a bacterial
pathogen, are two clinically relevant biofilm-forming microbes responsible for a majority of …

Coagulase-negative staphylococci (CoNS) are the main causative agents of bacteraemia in
infants managed in neonatal intensive care units (NICUs). Intraluminal colonization of long …

Background. Interdialytic locking of catheters with antimicrobial agents is frequently used for
preventing catheter-related infections, often associated with biofilm formation. We …

Antimicrobial catheter lock therapy is practiced to prevent lumenal-sourced infections of
central venous catheters. Citrate has been used clinically as an anticoagulant in heparin …

Central venous access devices (CVADs) are an essential component of modern health care.
However, their prolonged use commonly results in microbial colonization, which carries the …

Antimicrobial lock solutions may be needed to salvage indwelling catheters in patients
requiring continuous intravenous therapy. We determined the activity of minocycline, EDTA …

Biofilms that develop on indwelling devices are a major concern in clinical settings. While
removal of colonized devices remains the most frequent strategy for avoiding device-related …

Biofilms on catheters are responsible for catheter-related bloodstream infections (CRBSIs),
which cause significant mortality and morbidity. Antimicrobial catheter-lock solutions may …

The widespread use of intravascular devices, such as central venous and hemodialysis
catheters, in the past 2 decades has paralleled the increasing incidence of catheter-related …

Objectives Candida infections associated with catheters remain difficult to manage.
Antifungal lock strategies could be a therapeutic option when the device is difficult to remove …