Drug-eluting stents are the treatment of choice for reducing restenosis rates after plaque
removal. The drugs in use today partition between the plasma phase and binding sites in the …

Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart
disease, there remains considerable scope for the development of enhanced designs which …

Methods We construct a computational model of the drug transport within the arterial wall.
The governing equations, along with the suitable boundary conditions, are solved …

The development of restenosis within the coronary arteries after a stenting procedure has
been addressed with the development of the drug eluting stent device. However, in recent …

Atherosclerotic plaque formation due to lipid accumulation in the arterial wall is the major
cause of stenotic coronary disease. To restore distal coronary blood supply and overcome …

Drug-eluting stents are accepted as mainstream endovascular therapy, yet concerns for their
safety may be under-appreciated. While failure from restenosis has dropped to below 5 …

In the context of drug eluting stent, we present two-dimensional numerical models of mass
transport of the drug in the wall and in the lumen to study the effect of the drug diffusion …

In the last decade, many computational models have been developed to describe the
transport of drug eluted from stents and the subsequent uptake into arterial tissue. Each of …

In-stent restenosis occurs in coronary arteries after implantation of drug-eluting stents with
non-uniform restenosis thickness distribution in the artery cross section. Knowledge of the …

Drug-eluting stents have significantly improved the treatment of coronary artery disease.
They offer reduced rates of restenosis compared with their bare-metal predecessors and are …