[PDF][PDF] Metal sensing by the IRT1 transporter-receptor orchestrates its own degradation and plant metal nutrition

G Dubeaux, J Neveu, E Zelazny, G Vert - Molecular cell, 2018 - cell.com
Plant roots forage the soil for iron, the concentration of which can be dramatically lower than
those needed for growth. Soil iron uptake uses the broad metal spectrum IRT1 transporter …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

Dynamic control of the high-affinity iron uptake complex in root epidermal cells

A Martín-Barranco, J Spielmann, G Dubeaux… - Plant …, 2020 - academic.oup.com
In plants, iron uptake from the soil is tightly regulated to ensure optimal growth and
development. Iron absorption in Arabidopsis root epidermal cells requires the IRT1 …

Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis

M Barberon, G Dubeaux, C Kolb… - Proceedings of the …, 2014 - National Acad Sciences
In plants, the controlled absorption of soil nutrients by root epidermal cells is critical for
growth and development. IRON-REGULATED TRANSPORTER 1 (IRT1) is the main root …

IRT1, an Arabidopsis transporter essential for iron uptake from the soil and for plant growth

G Vert, N Grotz, F Dédaldéchamp, F Gaymard… - The plant …, 2002 - academic.oup.com
Plants are the principal source of iron in most diets, yet iron availability often limits plant
growth. In response to iron deficiency, Arabidopsis roots induce the expression of the …

The bifunctional transporter‐receptor IRT 1 at the heart of metal sensing and signalling

V Cointry, G Vert - New Phytologist, 2019 - Wiley Online Library
Transporters are at the centre of regulatory modules allowing optimal assimilation,
distribution or efflux of substrate molecules. The IRT 1 root metal transporter represents a …

Altered selectivity in an Arabidopsis metal transporter

EE Rogers, DJ Eide… - Proceedings of the …, 2000 - National Acad Sciences
Plants require metals for essential functions ranging from respiration to photosynthesis.
These metals also contribute to the nutritional value of plants for both humans and livestock …

IRT1 DEGRADATION FACTOR1, a RING E3 Ubiquitin Ligase, Regulates the Degradation of IRON-REGULATED TRANSPORTER1 in Arabidopsis

LJ Shin, JC Lo, GH Chen, J Callis, H Fu… - The Plant Cell, 2013 - academic.oup.com
Fe is an essential micronutrient for plant growth and development; plants have developed
sophisticated strategies to acquire ferric Fe from the soil. Nongraminaceous plants acquire …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …