The secreted frizzled-related protein 5 gene (SFRP5) that antagonize the Wnt/β-catenin
signaling is frequently inactivated by promoter methylation and oncogenic activation of the …

Tumor invasion and metastasis are closely associated with epithelial‑mesenchymal
transition (EMT). EMT refers to epithelial cells under physiological and pathological …

Oncogenic activation of the Wnt signaling pathway is common in cancers, but mutation of β‐
catenin in ovarian cancer is rare. In addition to genetic events, epigenetic modification of …

Background Contrary to the advantageous anticancer activities of curcumin (Cur), limited
bioavailability and solubility hindered its efficacy. Here, nontoxic dendrosomal nano carrier …

Abnormal activation of the Wnt/β-catenin signaling pathway and subsequent upregulation of
β-catenin driven downstream targets—c-Myc and cyclin D1 is associated with development …

As one main active compound of curcuminoids, Bisdemethoxycurcumin (BDMC) possesses
several biological activities, such as anti-inflammation and anti-cancer activities. However …

Objective: The current study aimed to explore the effect of curcumin on androgen receptor
(AR) expression in endometrial carcinoma cells, as well as the underlying mechanisms …

Background Curcumin has well-known, explicit biological anti-tumor properties. The Wnt/β-
catenin signaling pathway plays a central role in tumor cell proliferation and curcumin can …

Purpose: Curcumin, a component of turmeric, has been shown to suppress inflammation
and angiogenesis largely by inhibiting the transcription factor nuclear factor-κB (NF-κB). This …

Cervical cancer is the major cause of cancer related deaths in women, especially in
developing countries and Human Papilloma Virus infection in conjunction with multiple …