Regulation of carcinogenesis and modulation through Wnt/β-catenin signaling by curcumin in an ovarian cancer cell line
HY Yen, CW Tsao, YW Lin, CC Kuo, CH Tsao… - Scientific reports, 2019 - nature.com
The secreted frizzled-related protein 5 gene (SFRP5) that antagonize the Wnt/β-catenin
signaling is frequently inactivated by promoter methylation and oncogenic activation of the …
signaling is frequently inactivated by promoter methylation and oncogenic activation of the …
Curcumin inhibits tumor epithelial‑mesenchymal transition by downregulating the Wnt signaling pathway and upregulating NKD2 expression in colon cancer cells
Z Zhang, H Chen, C Xu, L Song… - Oncology …, 2016 - spandidos-publications.com
Tumor invasion and metastasis are closely associated with epithelial‑mesenchymal
transition (EMT). EMT refers to epithelial cells under physiological and pathological …
transition (EMT). EMT refers to epithelial cells under physiological and pathological …
Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway
Oncogenic activation of the Wnt signaling pathway is common in cancers, but mutation of β‐
catenin in ovarian cancer is rare. In addition to genetic events, epigenetic modification of …
catenin in ovarian cancer is rare. In addition to genetic events, epigenetic modification of …
Synergistic effects of dendrosomal nanocurcumin and oxaliplatin on oncogenic properties of ovarian cancer cell lines by down-expression of MMPs
E Seyed Hosseini, M Alizadeh Zarei… - Biological Research, 2023 - Springer
Background Contrary to the advantageous anticancer activities of curcumin (Cur), limited
bioavailability and solubility hindered its efficacy. Here, nontoxic dendrosomal nano carrier …
bioavailability and solubility hindered its efficacy. Here, nontoxic dendrosomal nano carrier …
Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/β-catenin signaling
Abnormal activation of the Wnt/β-catenin signaling pathway and subsequent upregulation of
β-catenin driven downstream targets—c-Myc and cyclin D1 is associated with development …
β-catenin driven downstream targets—c-Myc and cyclin D1 is associated with development …
Bisdemethoxycurcumin inhibits ovarian cancer via reducing oxidative stress mediated MMPs expressions
H Pei, Y Yang, L Cui, J Yang, X Li, Y Yang, H Duan - Scientific reports, 2016 - nature.com
As one main active compound of curcuminoids, Bisdemethoxycurcumin (BDMC) possesses
several biological activities, such as anti-inflammation and anti-cancer activities. However …
several biological activities, such as anti-inflammation and anti-cancer activities. However …
[PDF][PDF] Curcumin promotes the apoptosis of human endometrial carcinoma cells by downregulating the expression of androgen receptor through Wnt signal pathway.
W Feng, CX Yang, L Zhang, Y Fang… - Eur. J. Gynaec. Oncol …, 2017 - article.imrpress.com
Objective: The current study aimed to explore the effect of curcumin on androgen receptor
(AR) expression in endometrial carcinoma cells, as well as the underlying mechanisms …
(AR) expression in endometrial carcinoma cells, as well as the underlying mechanisms …
[HTML][HTML] Curcumin inhibits gastric carcinoma cell growth and induces apoptosis by suppressing the Wnt/β-catenin signaling pathway
R Zheng, Q Deng, Y Liu, P Zhao - Medical science monitor …, 2017 - ncbi.nlm.nih.gov
Background Curcumin has well-known, explicit biological anti-tumor properties. The Wnt/β-
catenin signaling pathway plays a central role in tumor cell proliferation and curcumin can …
catenin signaling pathway plays a central role in tumor cell proliferation and curcumin can …
Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-κB pathway
YG Lin, AB Kunnumakkara, A Nair, WM Merritt… - Clinical Cancer …, 2007 - AACR
Purpose: Curcumin, a component of turmeric, has been shown to suppress inflammation
and angiogenesis largely by inhibiting the transcription factor nuclear factor-κB (NF-κB). This …
and angiogenesis largely by inhibiting the transcription factor nuclear factor-κB (NF-κB). This …
Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells
PC Thacker, D Karunagaran - PloS one, 2015 - journals.plos.org
Cervical cancer is the major cause of cancer related deaths in women, especially in
developing countries and Human Papilloma Virus infection in conjunction with multiple …
developing countries and Human Papilloma Virus infection in conjunction with multiple …
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