Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis

D Szukiewicz - Vitamins and Hormones, 2023 - Elsevier
Endometriosis is a term referring to a condition whereby the endometrial tissue is found
outside the uterine cavity. This progressive and debilitating condition affects up to 15% of …

[HTML][HTML] Estrogen-and progesterone (P4)-mediated epigenetic modifications of endometrial stromal cells (EnSCs) and/or mesenchymal stem/stromal cells (MSCs) in …

D Szukiewicz, A Stangret, C Ruiz-Ruiz… - Stem Cell Reviews and …, 2021 - Springer
Endometriosis is a common chronic inflammatory condition in which endometrial tissue
appears outside the uterine cavity. Because ectopic endometriosis cells express both …

Oestrogen, progesterone and stem cells: the discordant trio in endometriosis?

CJ Susheelamma, SM Pillai, SA Nair - Expert reviews in molecular …, 2018 - cambridge.org
Oestrogen–progesterone signalling is highly versatile and critical for the maintenance of
healthy endometrium in humans. The genomic and nongenomic signalling cascades …

Endometrial adult/progenitor stem cells: pathogenetic theory and new antiangiogenic approach for endometriosis therapy

G Pittatore, A Moggio, C Benedetto… - Reproductive …, 2014 - journals.sagepub.com
The cyclical arrival of endometrial cells into the abdominal cavity through retrograde flux at
menstruation represents the etiopathogenetic basis of endometriosis. The endometrium has …

The pathogenesis of endometriosis: are endometrial stem/progenitor cells involved?

AS Laganà, A Naem - Stem Cells in Reproductive Tissues and Organs …, 2022 - Springer
Introduction: Endometriosis is an enigmatic disease defined by the presence of endometrial-
like glands and stroma out the uterine cavity. The pathogenesis of endometriosis was under …

Endometrial stem cells and endometriosis

S Canosa, AR Carosso, M Sestero, A Revelli… - Stem Cells in …, 2022 - Springer
Introduction: Endometrial stem/progenitor cells with functional properties of mesenchymal
stromal cells have been identified in a perivascular location of human endometrium. There is …

[HTML][HTML] Pathogenomics of endometriosis development

V Baranov, O Malysheva, M Yarmolinskaya - International journal of …, 2018 - mdpi.com
For over 100 years, endometriosis, as a chronic, estrogen-dependent, inflammatory,
heritable disease affecting approximately 5–10% of women in reproductive age has been …

[HTML][HTML] Cellular and molecular basis for endometriosis-associated infertility

JAW Stilley, JA Birt, KL Sharpe-Timms - Cell and tissue research, 2012 - Springer
Endometriosis is a gynecological disease characterized by the presence of endometrial
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …

Endometrial regeneration and endometrial stem/progenitor cells

CE Gargett, HPT Nguyen, L Ye - Reviews in Endocrine and Metabolic …, 2012 - Springer
The functional layer of the human endometrium is a highly regenerative tissue undergoing
monthly cycles of growth, differentiation and shedding during a woman's reproductive years …

[PDF][PDF] The endometrial regeneration frontiers: from mechanisms to applications in regenerative medicine

C Amălinei, I Păvăleanu, A Grigoraş, ID Căruntu… - Rom J Morphol …, 2018 - rjme.ro
The endometrium is a unique and remarkable tissue characterized by a constant
regeneration activity and this has been speculative for scientists, regarding its mechanism …