Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder frequently accompanied
by cognitive dysfunction and affects nearly 30% of people with diabetes, is an independent …

Recently, increasing attention has been paid to diabetic encephalopathy, which is a frequent
diabetic complication and affects nearly 30% of diabetics. Because cognitive dysfunction …

When ascending to high altitude, it is a rigorous challenge to people who living in the low
altitude area to acclimatize to hypoxic environment. Hypoxia exposure can cause dramatic …

Metabolomics is expected to identify potential metabolites and related pathways, and further
reveal the underlying mechanisms of the transition from prediabetes to diabetes. In this …

Diabetic encephalopathy (DE) is one of the chronic complications of diabetes. Even then,
the molecular mechanism underlying DE remains unexplored. In this study, we have made …

Abstract Introduction Type 1 diabetes (T1D) causes cognitive decline and has been
associated with brain metabolic disorders, but its potential molecular mechanisms remain …

Abstract Lou, Bih-Show, Pei-Shan Wu, Yitong Liu, and Jong-Shyan Wang. Effects of acute
systematic hypoxia on human urinary metabolites using LC-MS-based metabolomics. High …

Diabetes is recognized as a risk factor for cognitive decline, but the underlying mechanisms
remain elusive. We aimed to identify the metabolic pathways altered in diabetes-associated …

Diabetes related cognitive dysfunction (DACD), one of the chronic complications of diabetes,
seriously affect the quality of life in patients and increase family burden. Although the initial …

Objectives. To investigate the risk factors for cognitive impairment in Chinese type 2
diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of …