[PDF][PDF] Metabolomic analysis identifies guanosine as an early biomarker in Diabetic Cognitive Dysfunction in high-altitude
J Shi - 2023 - scholar.archive.org
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder frequently accompanied
by cognitive dysfunction and affects nearly 30% of people with diabetes, is an independent …
by cognitive dysfunction and affects nearly 30% of people with diabetes, is an independent …
Urine metabonomics reveals early biomarkers in diabetic cognitive dysfunction
L Song, P Zhuang, M Lin, M Kang, H Liu… - Journal of proteome …, 2017 - ACS Publications
Recently, increasing attention has been paid to diabetic encephalopathy, which is a frequent
diabetic complication and affects nearly 30% of diabetics. Because cognitive dysfunction …
diabetic complication and affects nearly 30% of diabetics. Because cognitive dysfunction …
[HTML][HTML] Metabolomic analysis of human plasma sample after exposed to high altitude and return to sea level
J Gao, M Zhao, X Cheng, X Yue, F Hao, H Wang… - PLoS …, 2023 - journals.plos.org
When ascending to high altitude, it is a rigorous challenge to people who living in the low
altitude area to acclimatize to hypoxic environment. Hypoxia exposure can cause dramatic …
altitude area to acclimatize to hypoxic environment. Hypoxia exposure can cause dramatic …
Activation of protein kinase A signaling and inhibitions of glycine/glutathione biosynthesis involves in the transition from prediabetes to diabetes based on …
N Zhao, Z Gu, L Li, M Jiang, W Chen, B Liu, J Zhu… - 2020 - researchsquare.com
Metabolomics is expected to identify potential metabolites and related pathways, and further
reveal the underlying mechanisms of the transition from prediabetes to diabetes. In this …
reveal the underlying mechanisms of the transition from prediabetes to diabetes. In this …
A novel hippocampus metabolite signature in diabetes mellitus rat model of diabetic encephalopathy
G Chen, Y Wang, Y Li, L Zhang, M Dong - Metabolic Brain Disease, 2020 - Springer
Diabetic encephalopathy (DE) is one of the chronic complications of diabetes. Even then,
the molecular mechanism underlying DE remains unexplored. In this study, we have made …
the molecular mechanism underlying DE remains unexplored. In this study, we have made …
[HTML][HTML] Optimized integration of metabolomics and lipidomics reveals brain region-specific changes of oxidative stress and neuroinflammation in type 1 diabetic mice …
F Xiong, K Gong, H Xu, Y Tu, J Lu, Y Zhou, W He… - Journal of Advanced …, 2023 - Elsevier
Abstract Introduction Type 1 diabetes (T1D) causes cognitive decline and has been
associated with brain metabolic disorders, but its potential molecular mechanisms remain …
associated with brain metabolic disorders, but its potential molecular mechanisms remain …
Effects of acute systematic hypoxia on human urinary metabolites using LC-MS-based metabolomics
BS Lou, PS Wu, Y Liu, JS Wang - High altitude medicine & biology, 2014 - liebertpub.com
Abstract Lou, Bih-Show, Pei-Shan Wu, Yitong Liu, and Jong-Shyan Wang. Effects of acute
systematic hypoxia on human urinary metabolites using LC-MS-based metabolomics. High …
systematic hypoxia on human urinary metabolites using LC-MS-based metabolomics. High …
[HTML][HTML] Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive …
NS Al-Akl, O Khalifa, G Ponirakis, A Parray… - International Journal of …, 2024 - mdpi.com
Diabetes is recognized as a risk factor for cognitive decline, but the underlying mechanisms
remain elusive. We aimed to identify the metabolic pathways altered in diabetes-associated …
remain elusive. We aimed to identify the metabolic pathways altered in diabetes-associated …
[HTML][HTML] Plasma metabolomic profiling of patients with diabetes-associated cognitive decline
L Zhang, M Li, L Zhan, X Lu, L Liang, B Su, H Sui… - PLoS …, 2015 - journals.plos.org
Diabetes related cognitive dysfunction (DACD), one of the chronic complications of diabetes,
seriously affect the quality of life in patients and increase family burden. Although the initial …
seriously affect the quality of life in patients and increase family burden. Although the initial …
Risk factors for cognitive impairment in patients with type 2 diabetes
L Sun, X Diao, X Gang, Y Lv, X Zhao… - Journal of diabetes …, 2020 - Wiley Online Library
Objectives. To investigate the risk factors for cognitive impairment in Chinese type 2
diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of …
diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of …
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