The gut harbors an enormous diversity of microbes that are essential for the maintenance of
homeostasis in health and disease. A growing body of evidence supports the role of this …

The gastrointestinal (GI) tract is a highly specialized sensory organ that provides crucial
negative feedback during a meal, partly via a gut–brain axis. More specifically …

Background Gut microbiota have recently been implicated in the pathogenesis of the obesity
and its related metabolic diseases. A variety of factors including diet, genetic background …

Western diets, with high consumption of simple sugars and saturated fats, contribute to the
rise in the prevalence of obesity. It now seems clear that high‐fat diets cause obesity, at least …

The gut microbiota has the capacity to affect host appetite via intestinal satiety pathways, as
well as complex feeding behaviors. In this Review, we highlight recent evidence that the gut …

The human gastrointestinal tract harbors trillions of bacteria, most of which are commensal
and have adapted over time to the milieu of the human colon. Their many metabolic …

The realization that the microbiota–gut–brain axis plays a critical role in health and disease
has emerged over the past decade. The brain–gut axis is a bidirectional communication …

Gut microbiota play an important role in maintaining intestinal health and are involved in the
metabolism of carbohydrates, lipids, and amino acids. Recent studies have shown that the …

Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

Obesity currently represents a major societal and health challenge worldwide. Its prevalence
has reached epidemic proportions and trends continue to rise, reflecting the need for more …