Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …

The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …

From a biological perspective, humans differ in the speed they age, and this may manifest in
both mental and physical health disparities. The discrepancy between an individual's …

Brain age is a metric that quantifies the degree of aging of a brain based on whole-brain
anatomical characteristics. While associations between individual human brain regions and …

Ageing is a heterogeneous multisystem process involving different rates of decline in
physiological integrity across biological systems. The current study dissects the unique and …

Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …

Brain imaging can be used to study how individuals' brains are aging, compared against
population norms. This can inform on aspects of brain health; for example, smoking and …

It is well established that brain structures and cognitive functions change across the life
span. A long-standing hypothesis called “age differentiation” additionally posits that the …

The association of the degree of aging based on the whole-brain anatomical characteristics,
or brain age, with smoking, alcohol consumption, and individual genetic variants is unclear …

Biological aging is revealed by physical measures, eg, DNA probes or brain scans.
Individual differences in personal functioning are instead explained by psychological …