A string of nucleotides confined within a protein capsid contains all the instructions
necessary to make a functional virus particle, a virion. Although the structure of the protein …

Lambda-like double-stranded (ds) DNA bacteriophage undergo massive conformational
changes in their capsid shell during the packaging of their viral genomes. Capsid shells are …

Large-scale conformational changes transform viral precursors into infectious virions. The
structure of bacteriophage HK97 capsid, Head-II, was recently solved by crystallography …

The all-atom model of an MS2 bacteriophage particle without its genome (the capsid) was
built using high-resolution cryo-electron microscopy (EM) measurements for initial …

The critical viral components for packaging DNA, recognizing and binding to host cells, and
injecting the condensed DNA into the host are organized at a single vertex of many …

The capsids of double-stranded DNA viruses protect the viral genome from the harsh
extracellular environment, while maintaining stability against the high internal pressure of …

Small viruses that belong, for example, to the Picornaviridae, such as poliovirus and foot-
and-mouth disease virus, consist simply of capsid proteins and a single-stranded RNA …

Packaging of genetic material inside a capsid is one of the major processes in the lifecycle
of bacteriophages. To establish the basic principles of packing double-stranded DNA into a …

Simulations of complete virus capsid at atomistic details have been performed using
standard molecular dynamics as well as original hybrid molecular dynamics/hydrodynamics …

Viruses protect their genetic information by enclosing the viral nucleic acid inside a protein
shell (capsid), in a process known as genome packaging. Viruses follow essentially two …