As lung cancer remains the leading cause of cancer deaths globally, characterizing the
tumor molecular profiles is crucial to tailoring treatments for individuals at advanced stages …

Chemoresistance is the leading cause of poor prognosis in head and neck squamous cell
carcinoma (HNSC); however, promising biomarkers to identify patients for stratified …

Background: Ferroptosis is an iron-dependent programmed cell death process. Recent
studies have found that ferroptosis inducers hold promising potential in the treatment of lung …

Introduction Iron metabolism is tightly controlled in human cells. Dysregulation of iron
metabolism-related genes has been characterized as a promising prognostic biomarker in …

Ferritin is the most important iron storage form and is known to influence tumor immunity. We
previously showed that expression of ferritin light chain (FTL) and ferritin heavy chain (FTH1) …

Background Ferroptosis is a newly identified type of programmed cell death, which
preferentially targets iron-rich cancer cells such as hepatocellular carcinoma (HCC). Ferritin …

Background Nuclear factor erythroid 2-related factor 2 (NFE2L2) plays a critical role in
ferroptosis and biogenesis, however, its role in cervical squamous cell carcinoma (CESC) …

Background In recent years, immunotherapies and targeted therapies contribute to
population-level improvement in NSCLC cancer-specific survival, however, the two novel …

Background CDGSH iron sulfur domain 2 (CISD2) is an iron–sulfur protein with a [2Fe–2S]
cluster, which is critical for cell proliferation and iron homeostasis. It has been demonstrated …

Background: Lung adenocarcinoma (LUAD) is a heterogeneous disease characterized by
high mortality and poor prognosis. Ferroptosis, a newly discovered iron-dependent type of …