Feature Selection and mRNA-miRNA bipartite Network Analysis for Biomarker Development and Drug Repurposing in Colon Cancer
Background: Colon cancer (CC) is the second cause of mortality among other non-skin
cancers. Despite the progression in screening and diagnostic strategies, further information …
cancers. Despite the progression in screening and diagnostic strategies, further information …
mRNA–miRNA bipartite network reconstruction to predict prognostic module biomarkers in colorectal cancer stage differentiation
Biomarker detection is one of the most important and challenging problems in cancer
studies. Recently, non-coding RNA based biomarkers such as miRNA expression levels …
studies. Recently, non-coding RNA based biomarkers such as miRNA expression levels …
Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis
X Zhou, X Huang, S Liang, S Tang, S Wu… - OncoTargets and …, 2018 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the fourth most common cause of cancer-related
mortality worldwide. The tumor, node, metastasis (TNM) stage remains the standard for CRC …
mortality worldwide. The tumor, node, metastasis (TNM) stage remains the standard for CRC …
[HTML][HTML] Identification of potential gene and microRNA biomarkers for colon cancer by an integrated bioinformatical approach
Q Ma, J Song, Z Chen, L Li, B Wang… - Translational Cancer …, 2018 - tcr.amegroups.org
Background: A unique resource for genomic studies is the NCI-60 cancer cell line panel,
which provides various publicly available datasets, including gene and microRNA (miRNA) …
which provides various publicly available datasets, including gene and microRNA (miRNA) …
Identification and Validation of Key miRNAs for Colon Cancer Based on miRNA-Gene Integration Analysis
Y Ji, J Gu, H Zhang, H Xu - International Journal of General …, 2023 - Taylor & Francis
Background MicroRNAs (miRNAs) plays an essential role in the pathogenesis of colon
cancer. This study aims to identify and verify key miRNAs that may serve as potential …
cancer. This study aims to identify and verify key miRNAs that may serve as potential …
Drug repurposing analysis for colorectal cancer through network medicine framework: Novel candidate drugs and small molecules
This study aimed to reveal the drug-repurposing candidates for colorectal cancer (CRC) via
drug-repurposing methods and network biology approaches. A novel, differentially co …
drug-repurposing methods and network biology approaches. A novel, differentially co …
[HTML][HTML] Co-modulated behavior and effects of differentially expressed miRNA in colorectal cancer
Background MicroRNAs (miRNAs) are short noncoding RNAs (approximately 22
nucleotides in length) that play important roles in colorectal cancer (CRC) progression …
nucleotides in length) that play important roles in colorectal cancer (CRC) progression …
[HTML][HTML] Identification and interaction analysis of molecular markers in colorectal cancer by integrated bioinformatics analysis
B Han, D Feng, X Yu, Y Zhang, Y Liu… - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Results A total of 264 DEGs and 8 DEMs were obtained. GO analysis revealed that the
DEGs were enriched in terms of cell structure, digestion, receptor binding, and extracellular …
DEGs were enriched in terms of cell structure, digestion, receptor binding, and extracellular …
[HTML][HTML] Revealing potential immunotherapy targets through analysis of a ceRNA network in human colon adenocarcinoma
C Li, Z Zhu, Q Hou, B Wang, L Zou, L Liu… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background Microsatellite instability-high (MSI-H) is a special type of human colon
adenocarcinoma (COAD) that responds well to immunotherapy. MicroRNAs (miRNAs) and …
adenocarcinoma (COAD) that responds well to immunotherapy. MicroRNAs (miRNAs) and …
Integrative analysis of molecular genetic targets and pathways in colorectal cancer through screening large-scale microarray data
E Onur, T Denkçeken - International Journal of Data Mining …, 2021 - inderscienceonline.com
Our aim was to make comprehensive analyses of mRNAs and miRNAs in early diagnosis of
Colorectal Cancer (CRC) via Principal Component Analysis (PCA)-based Unsupervised …
Colorectal Cancer (CRC) via Principal Component Analysis (PCA)-based Unsupervised …
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