Helicobacter pylori (H. pylori, ピロリ菌) は, 乳幼児期に経口的に体内に入ると,
何十年にもわたり胃粘膜に付着性の持続感染を成立させ, 萎縮性胃炎, 胃潰瘍 …

抄録 Helicobacter pylori (H. pylori) 持続感染モデルを用いた検討や多くの疫学的研究および除菌
による介入試験の結果から, H. pylori 感染と胃癌発症との関連性がほぼ確実視されている …

Many epidemiological studies have demonstrated a strong association between H. pylori
(Helicobacter pylori) infection and human gastric cancer development. The precise …

BACKGROUND/AIMS: The aim of this study was to study the role of Helicobacter pylori
infection and cagA expression in gastric carcinogenesis. METHODS One hundred forty six …

Genetic diversity within the cag pathogenicity island (PAI) of Helicobacter pylori may have a
modifying effect on the pathogenic potential of the infecting strain. The genetic structure of …

Infection with cagPAI positive strains of Helicobacter pylori is recognized as being
associated with an increased risk of gastric cancer. This article reviews the current …

Chronic infection with Helicobacter pylori is involved in a variety of clinical outcomes
including gastric cancer. In the present study, we focused on the infection strategies of H …

Gastric cancer is the second leading cause of cancer-related deaths worldwide (Parkinet al.
2001). Various epidemiologic studies identified a role for Helicobacter pylori in gastric …

Approximately half of the world's population is infected with the stomach pathogen
Helicobacter pylori. Infection with H. pylori is the main risk factor for distal gastric cancer …

Results The positivity of cagA was 97.4% in patients with gastric cancer, and 92.3% in
control subjects. Thirty-six strains (92.3%) isolated from patients and 35 strains (89.7%) from …