Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective …
Background After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …
GFAP-BDP as an acute diagnostic marker in traumatic brain injury: results from the prospective transforming research and clinical knowledge in traumatic brain injury …
DO Okonkwo, JK Yue, AM Puccio… - Journal of …, 2013 - liebertpub.com
Reliable diagnosis of traumatic brain injury (TBI) is a major public health need. Glial fibrillary
acidic protein (GFAP) is expressed in the central nervous system, and breakdown products …
acidic protein (GFAP) is expressed in the central nervous system, and breakdown products …
[HTML][HTML] Comparing glial fibrillary acidic protein (GFAP) in serum and plasma following mild traumatic brain injury in older adults
Objective: Identification and validation of blood-based biomarkers for the diagnosis and
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …
Glial fibrillary acidic protein in serum after traumatic brain injury and multiple trauma
LE Pelinka, A Kroepfl, R Schmidhammer… - Journal of Trauma …, 2004 - journals.lww.com
Background: This study aimed to determine whether glial fibrillary acidic protein (GFAP) is
released after traumatic brain injury (TBI), whether GFAP is related to brain injury severity …
released after traumatic brain injury (TBI), whether GFAP is related to brain injury severity …
Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed …
PJ McMahon, DM Panczykowski, JK Yue… - Journal of …, 2015 - liebertpub.com
Glial fibrillary acidic protein and its breakdown products (GFAP-BDP) are brain-specific
proteins released into serum as part of the pathophysiological response after traumatic brain …
proteins released into serum as part of the pathophysiological response after traumatic brain …
Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI
J Gill, L Latour, R Diaz-Arrastia, V Motamedi, C Turtzo… - Neurology, 2018 - AAN Enterprises
Objectives To determine whether a panel of blood-based biomarkers can discriminate
between patients with suspected mild traumatic brain injury (mTBI) with and without …
between patients with suspected mild traumatic brain injury (mTBI) with and without …
Glial fibrillary acidic protein is highly correlated with brain injury
KM Lumpkins, GV Bochicchio, K Keledjian… - Journal of Trauma …, 2008 - journals.lww.com
Background: Glial fibrillary acidic protein (GFAP) is an intermediate filament protein found in
the cytoskeleton of astroglia. Recent work has indicated that GFAP may serve as a serum …
the cytoskeleton of astroglia. Recent work has indicated that GFAP may serve as a serum …
Serum glial fibrillary acidic protein is a highly specific biomarker for traumatic brain injury in humans compared with S-100B and neuron-specific enolase
M Honda, R Tsuruta, T Kaneko… - Journal of Trauma …, 2010 - journals.lww.com
Background: Serum glial fibrillary acidic protein (GFAP) is a specific predictor of brain
damage and neurologic outcome in patients with traumatic brain injury (TBI). In this study …
damage and neurologic outcome in patients with traumatic brain injury (TBI). In this study …
Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study
JJ Bazarian, P Biberthaler, RD Welch… - The Lancet …, 2018 - thelancet.com
Background More than 50 million people worldwide sustain a traumatic brain injury (TBI)
annually. Detection of intracranial injuries relies on head CT, which is overused and …
annually. Detection of intracranial injuries relies on head CT, which is overused and …
Time course and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic …
L Papa, GM Brophy, RD Welch, LM Lewis… - JAMA …, 2016 - jamanetwork.com
Importance Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-
L1) have been widely studied and show promise for clinical usefulness in suspected …
L1) have been widely studied and show promise for clinical usefulness in suspected …
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