Abstract Background IgA nephropathy (IgAN) is a major cause of chronic kidney disease
(CKD). Renal interstitial fibrosis is a hallmark of CKD progression. Non-invasive biomarkers …

We evaluated biomarkers related to kidney fibrosis for the outcome of patients with IgA
nephropathy (IgAN). Clinical parameters (estimated glomerular filtration rate, hypertension …

Background Tumor necrosis factor alpha (TNF-α) is considered to play an important role in
the pathogenesis in IgA nephropathy (IgAN). The correlations between serum TNF-α and …

Background Renal fibrosis is the hallmark of progression to end-stage kidney disease. Non-
invasive biomarkers of renal fibrosis could serve as specific end points in clinical trials and …

Abstract Background IgA nephropathy (IgAN), the most common primary glomerulonephritis,
often presents as advanced renal failure with end-stage renal disease at diagnosis …

Abstract Primary IgA nephropathy (IgAN) diagnosis is based on IgA-dominant glomerular
deposits and histological scoring is done on formalin-fixed paraffin embedded tissue (FFPE) …

Background The worldwide prevalence of obesity is increasing. Obesity is associated with a
variety of chronic diseases, including chronic kidney disease. Several studies suggested …

Some patients diagnosed with benign IgA nephropathy (IgAN) develop a progressive
clinical course, not predictable by known clinical or histopathological parameters. To assess …

IgA nephropathy (IgAN) is the most frequent primary glomerulonephritis worldwide. Due to
its heterogenicity, there is a need to establish robust biomarkers for IgAN, to support …

Background The albumin-to-fibrinogen ratio (AFR), a novel inflammatory marker, has been
studied in various diseases. However, whether AFR could act as a prognostic factor for IgAN …