[HTML][HTML] Current understanding of fibrosis in genetic cardiomyopathies

TR Eijgenraam, HHW Silljé, RA de Boer - Trends in cardiovascular …, 2020 - Elsevier
Myocardial fibrosis is the excessive deposition of extracellular matrix proteins, including
collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or …

Myocardial fibrosis in congenital heart disease

RH Rathod, AJ Powell, T Geva - Circulation Journal, 2016 - jstage.jst.go.jp
Myocardial fibrosis is common in patients with congenital heart disease (CHD) and has
been associated with arrhythmias, decreased functional status, and adverse ventricular …

Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches

B López, S Ravassa, MU Moreno, GS José… - Nature Reviews …, 2021 - nature.com
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …

Myocardial fibrosis: biomedical research from bench to bedside

M Gyöngyösi, J Winkler, I Ramos, QT Do… - European journal of …, 2017 - Wiley Online Library
Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial
myocardial collagen network that occur in response to cardiac ischaemic insults, systemic …

Assessment of nonischemic myocardial fibrosis

C Jellis, J Martin, J Narula, TH Marwick - Journal of the American College of …, 2010 - jacc.org
Myocardial fibrosis is recognized as the pathologic entity of extracellular matrix remodeling.
Diffuse, reactive fibrosis is being increasingly recognized in a variety of conditions despite …

Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Myocardial fibrosis in congenital and pediatric heart disease

J Tian, X An, L Niu - Experimental and therapeutic …, 2017 - spandidos-publications.com
Cardiac fibrosis is a common phenomenon in different types of heart diseases, such as
ischemic heart disease, inherited cardiomyopathy mutations, diabetes, and ageing and is …

Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes

Q Xu, S Dewey, S Nguyen, AV Gomes - Journal of molecular and cellular …, 2010 - Elsevier
Cardiomyopathies, familial or sporadic, have become recognized as one of the leading
cardiac threats. Hypertrophic cardiomyopathy (HCM) affects 0.2% of the population and is …

Myocardial interstitial fibrosis in heart failure: biological and translational perspectives

A González, EB Schelbert, J Díez, J Butler - Journal of the American …, 2018 - jacc.org
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Myocardial fibrosis: why image, how to image and clinical implications

R Bing, MR Dweck - Heart, 2019 - heart.bmj.com
The current era has seen major advances in myocardial imaging. We are now able to
assess cardiac anatomy, function, tissue composition and disease activity across a wide …